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2079768-50-4

2079768-50-4 structure
2079768-50-4 structure
  • Name: Hydroxy-PEG5-acid
  • Chemical Name: 1-Hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
  • CAS Number: 2079768-50-4
  • Molecular Formula: C13H26O8
  • Molecular Weight: 310.341
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2021-01-06 13:28:44
  • Modify Date: 2025-08-28 15:56:15
  • Hydroxy-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 1-Hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
Synonyms 1-Hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
MFCD31380407
3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-hydroxy-
Description Hydroxy-PEG5-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.2±0.1 g/cm3
Boiling Point 455.7±45.0 °C at 760 mmHg
Molecular Formula C13H26O8
Molecular Weight 310.341
Flash Point 162.3±22.2 °C
Exact Mass 310.162781
LogP -2.42
Vapour Pressure 0.0±2.5 mmHg at 25°C
Index of Refraction 1.467
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