Conantokin-T

Modify Date: 2024-04-07 12:41:38

Conantokin-T Structure
Conantokin-T structure
Common Name Conantokin-T
CAS Number 127476-26-0 Molecular Weight 2683.81000
Density N/A Boiling Point N/A
Molecular Formula C110H175N31O45S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Conantokin-T


Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa[1].

 Names

Name Conantokin-T
Synonym More Synonyms

 Conantokin-T Biological Activity

Description Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa[1].
Related Catalog
Target

IC50: 2 μM (NMDA)[1]

In Vitro Conantokin-T produces a partial antagonism of NMDA receptor function with an IC50 value of 2 μM[1].
In Vivo Conantokin-T induces sleep-like symptoms in young mice[1].

 Chemical & Physical Properties

Molecular Formula C110H175N31O45S
Molecular Weight 2683.81000
Exact Mass 2682.21000
PSA 1338.87000
LogP 0.32530

 Synonyms

Conatokin t
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