127476-26-0
127476-26-0 structure
- Name: Conantokin-T
- Chemical Name: Conantokin-T
- CAS Number: 127476-26-0
- Molecular Formula: C110H175N31O45S
- Molecular Weight: 2683.81000
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
- Create Date: 2016-01-23 01:08:06
- Modify Date: 2024-04-07 12:41:38
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Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa[1].
| Name | Conantokin-T |
|---|---|
| Synonyms | Conatokin t |
| Description | Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 2 μM (NMDA)[1] |
| In Vitro | Conantokin-T produces a partial antagonism of NMDA receptor function with an IC50 value of 2 μM[1]. |
| In Vivo | Conantokin-T induces sleep-like symptoms in young mice[1]. |
| Molecular Formula | C110H175N31O45S |
|---|---|
| Molecular Weight | 2683.81000 |
| Exact Mass | 2682.21000 |
| PSA | 1338.87000 |
| LogP | 0.32530 |