Bis-propargyl-PEG3

Modify Date: 2025-08-25 23:15:29

Bis-propargyl-PEG3 Structure
Bis-propargyl-PEG3 structure
 Common Name Bis-propargyl-PEG3
CAS Number 126422-58-0 Molecular Weight 226.26900
Density N/A Boiling Point N/A
Molecular Formula C12H18O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-propargyl-PEG3


Bis-propargyl-PEG3 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG3 is used in the synthesis of zinc-dipicolylamine (ZnDPA) complexes with antiplasmodial activity[1] [2].

 Names

Name 3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]prop-1-yne
Synonym More Synonyms

 Bis-propargyl-PEG3 Biological Activity

Description Bis-propargyl-PEG3 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG3 is used in the synthesis of zinc-dipicolylamine (ZnDPA) complexes with antiplasmodial activity[1] [2].
Related Catalog
Target

PEGs

In Vitro Bis-propargyl-PEG3 is used in the synthesis of zinc-dipicolylamine (ZnDPA) complexes with antiplasmodial activity against three strains of Plasmodium falciparum [2].
References

[1]. Pearlie BURNETTE, et al. Dimeric immuno-modulatory compounds against cereblon-based mechanisms. WO2020014489A2.

[2]. Rice DR, et al. Antiplasmodial activity of targeted zinc(II)-dipicolylamine complexes. Bioorg Med Chem. 2017 May 15;25(10):2754-2760.

 Chemical & Physical Properties

Molecular Formula C12H18O4
Molecular Weight 226.26900
Exact Mass 226.12100
PSA 36.92000
LogP 0.31920

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

4,7,10,13-tetraoxahexadeca-1,15-diyne
4,7,10,13-tetraoxa-hexadeca-1,15-diine
Bis-propargyl-PEG3
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Chemsrc provides Bis-propargyl-PEG3(CAS#:126422-58-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Bis-propargyl-PEG3 are included as well.>> amp version: Bis-propargyl-PEG3

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