126422-58-0

126422-58-0 structure

Name: Bis-propargyl-PEG3
Chemical Name: 3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]prop-1-yne
CAS Number: 126422-58-0
Molecular Formula: C₁₂H₁₈O₄
Molecular Weight: 226.26900
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-11-04 00:01:20
Modify Date: 2024-01-16 18:24:59
Bis-propargyl-PEG3 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG3 is used in the synthesis of zinc-dipicolylamine (ZnDPA) complexes with antiplasmodial activity[1] [2].

Name	3-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]prop-1-yne
Synonyms	4,7,10,13-tetraoxahexadeca-1,15-diyne 4,7,10,13-tetraoxa-hexadeca-1,15-diine Bis-propargyl-PEG3

Description	Bis-propargyl-PEG3 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG3 is used in the synthesis of zinc-dipicolylamine (ZnDPA) complexes with antiplasmodial activity[1] [2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	Bis-propargyl-PEG3 is used in the synthesis of zinc-dipicolylamine (ZnDPA) complexes with antiplasmodial activity against three strains of Plasmodium falciparum [2].
References	[1]. Pearlie BURNETTE, et al. Dimeric immuno-modulatory compounds against cereblon-based mechanisms. WO2020014489A2. [2]. Rice DR, et al. Antiplasmodial activity of targeted zinc(II)-dipicolylamine complexes. Bioorg Med Chem. 2017 May 15;25(10):2754-2760.

Precursor 2
106-96-7 112-27-6
DownStream 0