1351373-48-2

1351373-48-2 structure

1351373-48-2 structure

Name: Bis-propargyl-PEG11
Chemical Name: Bis-propargyl-PEG10
CAS Number: 1351373-48-2
Molecular Formula: C₂₆H₄₆O₁₁
Molecular Weight: 534.64
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2021-09-11 19:59:52
Modify Date: 2024-01-10 13:45:37
Bis-propargyl-PEG10 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Bis-propargyl-PEG10

Description	Bis-propargyl-PEG10 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₆H₄₆O₁₁
Molecular Weight	534.64