159428-42-9

159428-42-9 structure
159428-42-9 structure
  • Name: Bis-propargyl-PEG4
  • Chemical Name: 4,7,10,13,16-Pentaoxanonadeca-1,18-diyne
  • CAS Number: 159428-42-9
  • Molecular Formula: C14H22O5
  • Molecular Weight: 270.322
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-06-06 08:00:32
  • Modify Date: 2025-08-23 10:31:33
  • Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers[1][2].

Name 4,7,10,13,16-Pentaoxanonadeca-1,18-diyne
Synonyms MFCD22201533
4,7,10,13,16-Pentaoxanonadeca-1,18-diyne
Description Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers[1][2].
Related Catalog
In Vitro Bis-propargyl-PEG4 can be used in the synthesis of demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis[2].
References

[1]. Pearlie BURNETTE, et al. Dimeric immuno-modulatory compounds against cereblon-based mechanisms. WO2020014489A2.

[2]. Jiang, et al. Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis. Tetrahedron, 2018: 74(27), 3527–3533.

Density 1.0±0.1 g/cm3
Boiling Point 338.7±37.0 °C at 760 mmHg
Molecular Formula C14H22O5
Molecular Weight 270.322
Flash Point 130.7±26.4 °C
Exact Mass 270.146729
LogP -0.41
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.463
Hazard Codes Xi
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