Bis-propargyl-PEG2

Modify Date: 2024-01-21 12:22:02

Bis-propargyl-PEG2 Structure
Bis-propargyl-PEG2 structure
Common Name Bis-propargyl-PEG2
CAS Number 126422-57-9 Molecular Weight 182.21600
Density 1.02g/mL Boiling Point 103 °C/0.8kPa
Molecular Formula C10H14O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-propargyl-PEG2


Bis-propargyl-PEG2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG2 is used for the synthesis of demethylvancomycin dimers[1][2].

 Names

Name α,ω-bis(O-propargyl)diethylene glycol
Synonym More Synonyms

 Bis-propargyl-PEG2 Biological Activity

Description Bis-propargyl-PEG2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG2 is used for the synthesis of demethylvancomycin dimers[1][2].
Related Catalog
Target

PEGs

In Vitro Bis-propargyl-PEG2 can be used in the synthesis of demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis[2].
References

[1]. Shenoi RA, et al. Synthesis, characterization, and biocompatibility of biodegradable hyperbranched polyglycerols from acid-cleavable ketal group functionalized initiators. Biomacromolecules. 2012 Oct 8;13(10):3018-30.

[2]. Jiang, et al. Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis. Tetrahedron, 2018: 74(27), 3527–3533.

 Chemical & Physical Properties

Density 1.02g/mL
Boiling Point 103 °C/0.8kPa
Molecular Formula C10H14O3
Molecular Weight 182.21600
Exact Mass 182.09400
PSA 27.69000
LogP 0.30260

 Synonyms

3-[2-(2-prop-2-ynyloxyethoxy)ethoxy]propyne
bis-O-propargyl-di(ethylene glycol)
4,7,10-trioxahexadeca-1,12-diyne
4,7,10-trioxatrideca-1,12-diyne
bis(2-propynoxyethyl)ether
4,7,10-trioxatrideca-1,12-diine