Bis-propargyl-PEG12

Modify Date: 2025-08-27 11:21:59

Bis-propargyl-PEG12 Structure
Bis-propargyl-PEG12 structure
Common Name Bis-propargyl-PEG12
CAS Number 1351373-49-3 Molecular Weight 578.69
Density N/A Boiling Point N/A
Molecular Formula C28H50O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-propargyl-PEG12


Bis-propargyl-PEG11 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis-propargyl-PEG11

 Bis-propargyl-PEG12 Biological Activity

Description Bis-propargyl-PEG11 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C28H50O12
Molecular Weight 578.69
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