Ro 41-0960
Modify Date: 2024-01-02 23:14:40
Ro 41-0960 structure
|
Common Name | Ro 41-0960 | ||
|---|---|---|---|---|
| CAS Number | 125628-97-9 | Molecular Weight | 277.20500 | |
| Density | 1.536g/cm3 | Boiling Point | 489.9ºC at 760 mmHg | |
| Molecular Formula | C13H8FNO5 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 250.1ºC | |
Use of Ro 41-0960Ro 41-0960 is a selective catechol-O-methyltransferase(COMT) inhibitor[1]. |
| Name | (3,4-dihydroxy-5-nitrophenyl)-(2-fluorophenyl)methanone |
|---|---|
| Synonym | More Synonyms |
| Description | Ro 41-0960 is a selective catechol-O-methyltransferase(COMT) inhibitor[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.536g/cm3 |
|---|---|
| Boiling Point | 489.9ºC at 760 mmHg |
| Molecular Formula | C13H8FNO5 |
| Molecular Weight | 277.20500 |
| Flash Point | 250.1ºC |
| Exact Mass | 277.03900 |
| PSA | 103.35000 |
| LogP | 2.89930 |
| Vapour Pressure | 3.2E-10mmHg at 25°C |
| Index of Refraction | 1.656 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| RTECS | PC4952300 |
|
Organic cation transporter 3 contributes to norepinephrine uptake into perivascular adipose tissue.
Am. J. Physiol. Heart Circ. Physiol. 309 , H1904-14, (2015) Perivascular adipose tissue (PVAT) reduces vasoconstriction to norepinephrine (NE). A mechanism by which PVAT could function to reduce vascular contraction is by decreasing the amount of NE to which t... |
|
|
Mechanism of the Association between Na+ Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters.
J. Biol. Chem. 290 , 13992-4003, (2015) Neurotransmitter:sodium symporters (NSSs) terminate neurotransmission by Na(+)-dependent reuptake of released neurotransmitters. Previous studies suggested that Na(+)-binding reconfigures dynamically ... |
|
|
Elevated expression of catechol-O-methyltransferase is associated with labor and increased prostaglandin E2production by human fetal membranes
Am. J. Obstet. Gynecol. 201(5) , 496.e1-7, (2009) Objective The purpose of this study was to evaluate the expression and function of catechol-O-methyltransferase in human fetal membranes at term. |
| OR 1139 |
| 3,4-dihydroxy-5-nitrophenyl 2-fluorophenyl ketone |
| (3,4-Dihydroxy-5-nitrophenyl)(2-fluorophenyl)methanone |
| 2'-fluoro-3,4-dihydroxy-5-nitrobenzophenone |
| 3,4-dihydroxy-5-nitro-2'-fluorobenzophenone |
| Ro 41-0960 |
| 2'-Fluoro-3,4-dihydroxy-5-nitrobenzophenone |
| Methanone,(3,4-dihydroxy-5-nitrophenyl)(2-fluorophenyl) |