1312991-77-7

1312991-77-7 structure

Name: Ro 8-4304 hydrochloride
Chemical Name: Ro 8-4304 hydrochloride
CAS Number: 1312991-77-7
Molecular Formula: C₂₁H₂₄ClFN₂O₃
Molecular Weight: 406.88
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2021-05-04 12:02:07
Modify Date: 2025-08-24 17:00:31
Ro 8-4304 hydrochloride is a potent NMDA receptor antagonist. Ro 8-4304 hydrochloride is a NR2B selective, non-competitive, voltage-independent antagonist[1].

Name	Ro 8-4304 hydrochloride
Synonyms	Benzamide, 4-[3-[4-(4-fluorophenyl)-3,6-dihydro-1(2H)-pyridinyl]-2-hydroxypropoxy]-, hydrochloride (1:1) 4-{3-[4-(4-Fluorophenyl)-3,6-dihydropyridin-1(2H)-yl]-2-hydroxypropoxy}benzamide hydrochloride (1:1) 4-{3-[4-(4-Fluorophenyl)-3,6-dihydro-1(2H)-pyridinyl]-2-hydroxypropoxy}benzamide hydrochloride (1:1) Ro 8-4304 hydrochloride

Description	Ro 8-4304 hydrochloride is a potent NMDA receptor antagonist. Ro 8-4304 hydrochloride is a NR2B selective, non-competitive, voltage-independent antagonist[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Kew JN, et, al. State-dependent NMDA receptor antagonism by Ro 8-4304, a novel NR2B selective, non-competitive, voltage-independent antagonist. Br J Pharmacol. 1998 Feb;123(3):463-72.