Pleuromutilin
Pleuromutilin structure
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Common Name | Pleuromutilin | ||
|---|---|---|---|---|
| CAS Number | 125-65-5 | Molecular Weight | 378.502 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 482.8±45.0 °C at 760 mmHg | |
| Molecular Formula | C22H34O5 | Melting Point | 170-171ºC | |
| MSDS | Chinese USA | Flash Point | 158.7±22.2 °C | |
Use of Pleuromutilinpleuromutilin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria. |
| Name | Pleuromutilin |
|---|---|
| Synonym | More Synonyms |
| Description | pleuromutilin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 482.8±45.0 °C at 760 mmHg |
| Melting Point | 170-171ºC |
| Molecular Formula | C22H34O5 |
| Molecular Weight | 378.502 |
| Flash Point | 158.7±22.2 °C |
| Exact Mass | 378.240631 |
| PSA | 83.83000 |
| LogP | 2.63 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.538 |
| InChIKey | ZRZNJUXESFHSIO-FEOSZSLTSA-N |
| SMILES | C=CC1(C)CC(OC(=O)CO)C2(C)C(C)CCC3(CCC(=O)C32)C(C)C1O |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Hazard Codes | Xi |
|---|---|
| RIDADR | NONH for all modes of transport |
| RTECS | MC5408000 |
| HS Code | 2918199090 |
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Pleuromutilin CAS#:125-65-5 |
| Literature: Journal of the American Chemical Society, , vol. 111, # 21 p. 8284 - 8286 |
|
~%
Pleuromutilin CAS#:125-65-5 |
| Literature: Journal of the American Chemical Society, , vol. 111, # 21 p. 8284 - 8286 |
|
~%
Pleuromutilin CAS#:125-65-5 |
| Literature: Journal of the American Chemical Society, , vol. 111, # 21 p. 8284 - 8286 |
|
~%
Pleuromutilin CAS#:125-65-5 |
| Literature: Journal of the American Chemical Society, , vol. 111, # 21 p. 8284 - 8286 |
![(3S,3aR,4R,5R,7S,8S,9R,9aS,12R)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-3-ol structure](https://image.chemsrc.com/caspic/269/80878-40-6.png)
![(3aR,4R,5R,7S,8S,9R,9aS,12R)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyloctahydro-4,9a-propanocyclopenta[8]annulen-3(3aH)-one structure](https://image.chemsrc.com/caspic/231/80878-41-7.png)
![(3R,3aS,4S,5S,7R,8R,9S,9aR,12S)-3-(benzyloxy)-5,8-bis(methoxymethoxy)-4,7,9,12-tetramethyl-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulene structure](https://image.chemsrc.com/caspic/124/80878-39-3.png)
| HS Code | 2918199090 |
|---|---|
| Summary | 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Novel ABC transporter gene, vga(C), located on a multiresistance plasmid from a porcine methicillin-resistant Staphylococcus aureus ST398 strain.
Antimicrob. Agents Chemother. 53 , 3589-91, (2009) A novel ABC transporter gene, vga(C), was identified on the 14,365-bp multiresistance plasmid pKKS825 in a porcine methicillin (meticillin)-resistant Staphylococcus aureus isolate of sequence type 398... |
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Design, synthesis, and antibacterial activity of novel pleuromutilin derivatives bearing an amino thiazolyl ring.
Arch. Pharm. (Weinheim) 345(8) , 638-46, (2012) A series of novel pleuromutilin derivatives containing the amino thiazolyl ring were designed, synthesized, and evaluated for their antibacterial activities in vitro against Gram-positive clinical bac... |
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Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket.
Mol. Microbiol. 71(5) , 1218-27, (2009) Tiamulin and valnemulin target the peptidyl transferase centre (PTC) on the bacterial ribosome. They are used in veterinary medicine to treat infections caused by a variety of bacterial pathogens, inc... |
| Acetic acid, 2-hydroxy-, 6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester |
| Pleuromulin |
| Valnemulin impurity E |
| 5-Hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl hydroxyacetate |
| Drosophilin B,Mutilin 14-glycolate |
| EINECS 204-747-5 |
| 3-Hydroxy-2,4,7,14-tetramethyl-9-oxo-4-vinyltricyclo[5.4.3.0]tetradec-6-yl glycolate |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Pleuromutilin
- Price: Check
- Purity: 98.0%
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- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Pleuromutilin
- Price: ￥2088.0/500g ￥588.0/100g
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- DC Chemicals Limited
- China
- Product Name: Pleuromulin
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- Purity: 98.0%
- Delivery: 3 Day
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- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Pleuromulin
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
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- Email: enquiry@dycnchem.com
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Pleuromulin, 99%
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Delivery: Inquiry
- Contact: Anson
- Email: info@tianfuchem.com
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