Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Pleuromutilin
Price: ￥2088.0/500g ￥588.0/100g
Purity: 80.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Pleuromulin
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Pleuromulin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Pleuromulin
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Pleuromulin, 99%
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

125-65-5

125-65-5 structure

125-65-5 structure

Name: Pleuromutilin
Chemical Name: Pleuromutilin
CAS Number: 125-65-5
Molecular Formula: C₂₂H₃₄O₅
Molecular Weight: 378.502
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2018-03-28 08:00:00
Modify Date: 2024-01-02 01:19:44
pleuromutilin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.

Name	Pleuromutilin
Synonyms	Acetic acid, 2-hydroxy-, 6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester Pleuromulin Valnemulin impurity E 5-Hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl hydroxyacetate Drosophilin B,Mutilin 14-glycolate EINECS 204-747-5 3-Hydroxy-2,4,7,14-tetramethyl-9-oxo-4-vinyltricyclo[5.4.3.0]tetradec-6-yl glycolate

Description	pleuromutilin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection Natural Products >> Terpenoids and Glycosides
References	[1]. Shang RF et al. Synthesis and biological evaluation of new pleuromutilin derivatives as antibacterial agents. Molecules. 2014 Nov 19;19(11):19050-65.

Density	1.2±0.1 g/cm3
Boiling Point	482.8±45.0 °C at 760 mmHg
Melting Point	170-171ºC
Molecular Formula	C₂₂H₃₄O₅
Molecular Weight	378.502
Flash Point	158.7±22.2 °C
Exact Mass	378.240631
PSA	83.83000
LogP	2.63
Vapour Pressure	0.0±2.8 mmHg at 25°C
Index of Refraction	1.538

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MC5408000

CHEMICAL NAME :: Glycolic acid, 8-ester with octahydro-5,8-dihydroxy-4,6,9,10-tetramethyl-6-vinyl- 3a,9- propano-3aH-cyclopentacycloocten-1(4H)-one

CAS REGISTRY NUMBER :: 125-65-5

LAST UPDATED :: 199806

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C22-H34-O5

MOLECULAR WEIGHT :: 378.56

WISWESSER LINE NOTATION :: T568/EN 2AE N BV EXTJ H1 I1 JOV1Q L1U1 L1 MQ N1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 6,123,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 6,123,1981

Hazard Codes	Xi
RIDADR	NONH for all modes of transport
RTECS	MC5408000
HS Code	2918199090

80878-40-6 structure

80878-40-6

~%

125-65-5 structure

125-65-5

Literature: Journal of the American Chemical Society, , vol. 111, # 21 p. 8284 - 8286

80878-41-7 structure

80878-41-7

~%

125-65-5 structure

125-65-5

Literature: Journal of the American Chemical Society, , vol. 111, # 21 p. 8284 - 8286

80878-39-3 structure

80878-39-3

~%

125-65-5 structure

125-65-5

Literature: Journal of the American Chemical Society, , vol. 111, # 21 p. 8284 - 8286

123331-26-0 structure

123331-26-0

6040-37-5 structure

6040-37-5

~%

125-65-5 structure

125-65-5

Literature: Journal of the American Chemical Society, , vol. 111, # 21 p. 8284 - 8286

HS Code	2918199090
Summary	2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%