WAY208466 dihydrochloride

Modify Date: 2024-01-12 12:21:54

WAY208466 dihydrochloride Structure
WAY208466 dihydrochloride structure
Common Name WAY208466 dihydrochloride
CAS Number 1207064-61-6 Molecular Weight 420.329
Density N/A Boiling Point N/A
Molecular Formula C17H20Cl2FN3O2S Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of WAY208466 dihydrochloride


WAY 208466 dihydrochloride is a potent and selective 5-HT6 receptor agonist (EC50=7.3 nM for the human 5-HT6 receptor). WAY-208466 dihydrochloride elevates cortical GABA levels in rat frontal cortex[1]. WAY 208466 dihydrochloride exhibits antidepressant and anxiolytic-like effects[2].

 Names

Name WAY 208466 dihydrochloride
Synonym More Synonyms

 WAY208466 dihydrochloride Biological Activity

Description WAY 208466 dihydrochloride is a potent and selective 5-HT6 receptor agonist (EC50=7.3 nM for the human 5-HT6 receptor). WAY-208466 dihydrochloride elevates cortical GABA levels in rat frontal cortex[1]. WAY 208466 dihydrochloride exhibits antidepressant and anxiolytic-like effects[2].
Related Catalog
References

[1]. Schechter LE, et al. Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466. Neuropsychopharmacology. 2008 May;33(6):1323-35.

[2]. Carr GV, Schechter LE, Lucki I. Antidepressant and anxiolytic effects of selective 5-HT6 receptor agonists in rats. Psychopharmacology (Berl). 2011 Feb;213(2-3):499-507.

 Chemical & Physical Properties

Molecular Formula C17H20Cl2FN3O2S
Molecular Weight 420.329
Exact Mass 419.063721

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P305 + P351 + P338
RIDADR NONH for all modes of transport

 Synonyms

MFCD20926423
2-{3-[(3-Fluorophenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-1-yl}-N,N-dimethylethanamine dihydrochloride
WAY 208466 dihydrochloride
WAY-208466 (hydrochloride)
1H-Pyrrolo[2,3-b]pyridine-1-ethanamine, 3-[(3-fluorophenyl)sulfonyl]-N,N-dimethyl-, hydrochloride (1:2)
WAY-208466 DIHYDROCHLORIDE
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