86694-45-3

86694-45-3 structure

Name: preQ1 Dihydrochloride
Chemical Name: 2-amino-5-(aminomethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one dihydrochloride
CAS Number: 86694-45-3
Molecular Formula: C₇H₁₀ClN₅O
Molecular Weight: 215.64000
Catalog: Research Areas Metabolic Disease
Create Date: 2018-01-23 05:07:25
Modify Date: 2025-09-03 23:31:19
preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity[1].

Name	2-amino-5-(aminomethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one dihydrochloride
Synonyms	7-aminomethyl-7-deazaguanine dihydrochloride preQ1 Dihydrochloride

Description	preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
References	[1]. Connelly CM, et al. Synthetic ligands for PreQ1 riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun. 2019 Apr 2;10(1):1501.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Hazard Codes	Xn
Risk Phrases	22-36/37/38
RIDADR	NONH for all modes of transport