ω-Conotoxin GVIA trifluoroacetate salt

Modify Date: 2024-01-02 17:20:54

ω-Conotoxin GVIA trifluoroacetate salt Structure
ω-Conotoxin GVIA trifluoroacetate salt structure
Common Name ω-Conotoxin GVIA trifluoroacetate salt
CAS Number 106375-28-4 Molecular Weight 3037.35000
Density 1.71 Boiling Point N/A
Molecular Formula C120H182N38O43S6 Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of ω-Conotoxin GVIA trifluoroacetate salt


ω-Conotoxin GVIA is an inhibitor of the N-type Ca2+ channel[1].

 Names

Name ω-Conotoxin GVIA
Synonym More Synonyms

 ω-Conotoxin GVIA trifluoroacetate salt Biological Activity

Description ω-Conotoxin GVIA is an inhibitor of the N-type Ca2+ channel[1].
Related Catalog
In Vitro ω-conotoxin GVIA (50 nM, 50 nL) inhibits the effects of urotensin II (UII)[1].
References

[1]. Ya-Kun Cao, et al. Microinjection of urotensin II into the rostral ventrolateral medulla increases sympathetic vasomotor tone via the GPR14/ERK pathway in rats. Hypertens Res. 2020 Aug;43(8):765-771.

 Chemical & Physical Properties

Density 1.71
Molecular Formula C120H182N38O43S6
Molecular Weight 3037.35000
Exact Mass 3035.15000
PSA 1496.38000
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR UN 3172
WGK Germany 3
RTECS GL2665050
Packaging Group III
Hazard Class 6.1(b)

 Articles2

More Articles
Differential blockade of rat alpha3beta4 and alpha7 neuronal nicotinic receptors by omega-conotoxin MVIIC, omega-conotoxin GVIA and diltiazem.

Br. J. Pharmacol. 127 , 1375, (1999)

Rat alpha3beta4 or alpha7 neuronal nicotinic acetylcholine receptors (AChRs) were expressed in Xenopus laevis oocytes, and the effects of various toxins and non-toxin Ca2+ channel blockers studied. Ni...

Spermine does not compete with omega-conotoxin GVIA in the striatum radiatum of the hippocampal slice.

Brain Res. 772 , 191, (1997)

The effect of spermine (Spm) and of omega-conotoxin GVIA (CTX) on the population excitatory postsynaptic potentials (pEPSP) in stratum radiatum of the CA1 area were compared. CTX decreased irreversibl...

 Synonyms

w-ConotoxinGVIA
w-Conotoxin GVIA,Conus geographus
o-Conotoxin GVIA
MFCD00076620
M.W. 3037.35 C120H182N38O43S6