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34592-47-7

34592-47-7 structure
34592-47-7 structure

Name L-Thioproline
Synonyms H-THZ-OH
L-Thiazolidine-4-car
(R)-4-Thiazolidinecarboxylic acid
EINECS 252-106-3
L-THC
THIAPROLINE
(4R)-4-Thiazolidinecarboxylic acid
(4R)-thiazolidine-4-carboxylic acid
1,3-Thiazolidine-2-carboxylic acid
Thiazolidinecarboxylic acid (VAN)
THIAZOLIDINECARBOXYLIC ACID
2-Thiazolidinecarboxylic acid
DL-Thiazolidinecarboxylic acid
L(-)-Thiazolidine-4-carboxylicacid
L(-)-Thiazolidine-4-Carboxylic Acid
L-Thiazolidine-4-carboxylic acid
H-L-THZ-OH
MFCD00005212
(4R)-1,3-Thiazolidine-4-carboxylic acid
L-4-Thiazolidinecarboxylic acid
L-Thioproline
thiazolidinecarboxylicacid
(R)-(-)-4-Thiazolidinecarboxylic acid
L- thiazolidine-4-carboxylic acid
THIOPROLINE
H-THIOPRO-OH
L-THIAPROLINE
(R)-Thiazolidine-4-carboxylic acid
(R)-(-)-Thiazolidine-4-carboxylic Acid
L-thiazoline-4-carboxylic acid
4-Thiazolidinecarboxylic acid, (4R)-
Description (R)-Thiazolidine-4-carboxylic acid is a proline derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Density 1.4±0.1 g/cm3
Boiling Point 350.3±37.0 °C at 760 mmHg
Melting Point 190-200 °C (dec.)(lit.)
Molecular Formula C4H7NO2S
Molecular Weight 133.169
Flash Point 165.7±26.5 °C
Exact Mass 133.019745
PSA 74.63000
LogP -0.39
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.566
Water Solubility 28.5 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ5425500
CHEMICAL NAME :
4-Thiazolidinecarboxylic acid, L-
CAS REGISTRY NUMBER :
34592-47-7
LAST UPDATED :
199610
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C4-H7-N-O2-S
MOLECULAR WEIGHT :
133.18
WISWESSER LINE NOTATION :
T5M CSTJ EVQ -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
210 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2547728
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
178 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00644
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H312-H315-H319-H332-H335
Precautionary Statements P261-P280-P301 + P310-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22
Safety Phrases S26-S36/37/39-S36
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS XJ5425500
Packaging Group III
Hazard Class 6.1(b)
HS Code 29341000

~98%

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34592-47-7

Literature: Kaupp, Gerd; Schmeyers, Jens; Boy, Juergen Tetrahedron, 2000 , vol. 56, # 36 p. 6899 - 6911

~93%

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34592-47-7

Literature: Refouvelet; Pellegrini; Robert; Crini; Blacque; Kubicki Journal of Heterocyclic Chemistry, 2000 , vol. 37, # 6 p. 1425 - 1430

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34592-47-7

Literature: US6605608 B1, ; US 6605608 B1

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34592-47-7

Literature: Journal of Biological Chemistry, , vol. 114, p. 348 Journal of Biological Chemistry, , vol. 121, p. 542,545

~78%

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34592-47-7

Literature: Shiraiwa, Tadashi; Kataoka, Kazuo; Kurokawa, Hidemoto Chemistry Letters, 1987 , p. 2041 - 2042

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Literature: Journal of Organic Chemistry, , vol. 74, # 11 p. 4289 - 4297

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34592-47-7

Literature: Tetrahedron, , vol. 51, # 10 p. 3015 - 3024

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Literature: Bulletin of the Chemical Society of Japan, , vol. 65, # 1 p. 267 - 273

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34592-47-7 structure

34592-47-7

Literature: Bulletin of the Chemical Society of Japan, , vol. 60, # 9 p. 3277 - 3284
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%