L-Thioproline

Modify Date: 2024-01-02 15:42:07

L-Thioproline structure	Common Name	L-Thioproline
	CAS Number	34592-47-7	Molecular Weight	133.169
	Density	1.4±0.1 g/cm3	Boiling Point	350.3±37.0 °C at 760 mmHg
	Molecular Formula	C₄H₇NO₂S	Melting Point	190-200 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	165.7±26.5 °C
	Symbol	GHS06	Signal Word	Danger

Use of L-Thioproline

(R)-Thiazolidine-4-carboxylic acid is a proline derivative[1].

Name	L-Thioproline
Synonym	More Synonyms

Description	(R)-Thiazolidine-4-carboxylic acid is a proline derivative[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References	[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Density	1.4±0.1 g/cm3
Boiling Point	350.3±37.0 °C at 760 mmHg
Melting Point	190-200 °C (dec.)(lit.)
Molecular Formula	C₄H₇NO₂S
Molecular Weight	133.169
Flash Point	165.7±26.5 °C
Exact Mass	133.019745
PSA	74.63000
LogP	-0.39
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.566
Water Solubility	28.5 g/L (20 ºC)

L-Thioproline MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ5425500

CHEMICAL NAME :: 4-Thiazolidinecarboxylic acid, L-

CAS REGISTRY NUMBER :: 34592-47-7

LAST UPDATED :: 199610

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C4-H7-N-O2-S

MOLECULAR WEIGHT :: 133.18

WISWESSER LINE NOTATION :: T5M CSTJ EVQ -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 210 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2547728

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 178 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00644

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301-H312-H315-H319-H332-H335
Precautionary Statements	P261-P280-P301 + P310-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22
Safety Phrases	S26-S36/37/39-S36
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	XJ5425500
Packaging Group	III
Hazard Class	6.1(b)
HS Code	29341000

Formaldehyde

CAS#:50-00-0

L-cysteine

CAS#:52-90-4

~98%

L-Thioproline

CAS#:34592-47-7

Literature: Kaupp, Gerd; Schmeyers, Jens; Boy, Juergen Tetrahedron, 2000 , vol. 56, # 36 p. 6899 - 6911

Formaldehyde

CAS#:50-00-0

L-Cysteine hydr...

CAS#:52-89-1

~93%

L-Thioproline

CAS#:34592-47-7

Literature: Refouvelet; Pellegrini; Robert; Crini; Blacque; Kubicki Journal of Heterocyclic Chemistry, 2000 , vol. 37, # 6 p. 1425 - 1430

L-cysteine

CAS#:52-90-4

L-Thioproline

CAS#:34592-47-7

Literature: US6605608 B1, ; US 6605608 B1

L-Cysteine hydr...

CAS#:52-89-1

L-Thioproline

CAS#:34592-47-7

Literature: Journal of Biological Chemistry, , vol. 114, p. 348 Journal of Biological Chemistry, , vol. 121, p. 542,545

(2S,3S)-2,3-dih...

CAS#:114192-99-3

~78%

L-Thioproline

CAS#:34592-47-7

Literature: Shiraiwa, Tadashi; Kataoka, Kazuo; Kurokawa, Hidemoto Chemistry Letters, 1987 , p. 2041 - 2042

N-Boc-(R)-(-)-t...

CAS#:51077-16-8

L-Thioproline

CAS#:34592-47-7

Literature: Journal of Organic Chemistry, , vol. 74, # 11 p. 4289 - 4297

(R)-1-aza-3-oxa...

CAS#:164986-91-8

L-Thioproline

CAS#:34592-47-7

Literature: Tetrahedron, , vol. 51, # 10 p. 3015 - 3024

Timonacic

CAS#:444-27-9

L-Thioproline

CAS#:34592-47-7

Literature: Bulletin of the Chemical Society of Japan, , vol. 65, # 1 p. 267 - 273

Formaldehyde

CAS#:50-00-0

DL-Cysteine Hyd...

CAS#:10318-18-0

Timonacic

CAS#:444-27-9

L-Thioproline

CAS#:34592-47-7

Literature: Bulletin of the Chemical Society of Japan, , vol. 60, # 9 p. 3277 - 3284

Precursor 7
CAS#:50-00-0 Formaldehyde CAS#:52-90-4 L-cysteine CAS#:52-89-1 L-Cysteine hydr... CAS#:114192-99-3 (2S,3S)-2,3-dih...
CAS#:51077-16-8 N-Boc-(R)-(-)-t... CAS#:444-27-9 Timonacic CAS#:10318-18-0 DL-Cysteine Hyd...
DownStream 10
CAS#:54323-50-1 (4R)-3-Acetyl-1... CAS#:50703-06-5 4-Thiazolidinec... CAS#:51077-16-8 N-Boc-(R)-(-)-t... CAS#:5025-82-1 Folcisteine
CAS#:52-90-4 L-cysteine CAS#:444-27-9 Timonacic CAS#:121808-62-6 Pidotimod CAS#:14344-46-8 3-mercapto-2-(m...
CAS#:122946-43-4 Telmesteine CAS#:70665-28-0 3-(1-oxidopyrid...

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).

Bioorg. Med. Chem. 19 , 6409-18, (2011)

The proton-coupled amino acid transporter hPAT1 has recently gained much interest due to its ability to transport small drugs thereby allowing their oral administration. A three-dimensional quantitati...

Design, synthesis and biological evaluation of 2-(substituted phenyl)thiazolidine-4-carboxylic acid derivatives as novel tyrosinase inhibitors.

Biochimie 94(2) , 533-40, (2012)

Herein we describe the design, synthesis and biological activities of 2-(substituted phenyl)thiazolidine-4-carboxylic acid derivatives as novel tyrosinase inhibitors. The target compounds 2a-2j were d...

Successful computer guided planned synthesis of (4R)-thiazolidine carboxylic acid and its 2-substituted analogues as urease inhibitors.

Mol. Divers. 10(2) , 223-31, (2006)

By using internal combinatorial library we were able to identify (4R)-thiazolidines carboxylic acid and its 2-substituted analogs as active inhibitors of urease. Molecular modeling and virtual screeni...

H-THZ-OH

L-Thiazolidine-4-car

(R)-4-Thiazolidinecarboxylic acid

EINECS 252-106-3

L-THC

THIAPROLINE

(4R)-4-Thiazolidinecarboxylic acid

(4R)-thiazolidine-4-carboxylic acid

1,3-Thiazolidine-2-carboxylic acid

Thiazolidinecarboxylic acid (VAN)

THIAZOLIDINECARBOXYLIC ACID

2-Thiazolidinecarboxylic acid

DL-Thiazolidinecarboxylic acid

L(-)-Thiazolidine-4-carboxylicacid

L(-)-Thiazolidine-4-Carboxylic Acid

L-Thiazolidine-4-carboxylic acid

H-L-THZ-OH

MFCD00005212

(4R)-1,3-Thiazolidine-4-carboxylic acid

L-4-Thiazolidinecarboxylic acid

L-Thioproline

thiazolidinecarboxylicacid

(R)-(-)-4-Thiazolidinecarboxylic acid

L- thiazolidine-4-carboxylic acid

THIOPROLINE

H-THIOPRO-OH

L-THIAPROLINE

(R)-Thiazolidine-4-carboxylic acid

(R)-(-)-Thiazolidine-4-carboxylic Acid

L-thiazoline-4-carboxylic acid

4-Thiazolidinecarboxylic acid, (4R)-

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: L-Thioproline
Price: ￥88.0/5g ￥258.0/25g ￥358.0/100g ￥788.0/500g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Timonacic
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: L-Thioproline
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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L-Thioproline

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