122946-43-4

122946-43-4 structure

Name: Telmesteine
Chemical Name: (4R)-3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid
CAS Number: 122946-43-4
Molecular Formula: C₇H₁₁NO₄S
Molecular Weight: 205.23
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-06-03 08:00:00
Modify Date: 2025-09-10 23:24:09
Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease[1][2].

Name	(4R)-3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid
Synonyms	(R)-3-(Ethoxycarbonyl)thiazolidine-4-carboxylic acid Telmesteinum Telmesteine (INN) Telmesteine Telmesteina (R)-thiazolidine-3,4-dicarboxylic acid-3-ethyl ester Reolase (TN) N-ethoxycarbonyl-D-thiazolidine-4-carboxylic acid (R)-Thiazolidin-3,4-dicarbonsaeure-3-aethylester Telmesteinum [INN-Latin] UNII-124I3FE35T

Description	Telmesteine is an amucolitic agent. Telmesteine has anti-protease activity. Telmesteine inhibits LPS-induced NO production in RAW264.7 cells. Telmesteine can be used for research of inflammation, such as acute and chronic bronchitis and obstructive airways disease[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Lee J, et al. Absorption, distribution, metabolism and excretion of telmesteine, a mucolitic agent, in rat. Xenobiotica. 2003 Jul;33(7):755-65. [2]. Xuetao Xu, et al. Evaluation of the anti-inflammatory properties of telmesteine on inflammation-associated skin diseases. RSC Adv., 2017, 7, 34699-34704.

HS Code	2934999090

541-41-3

34592-47-7

122946-43-4

Literature: Braibante, Mara E.F.; Braibante, Hugo S.; Costenaro, Edson R. Synthesis, 1999 , # 6 p. 943 - 946

541-41-3

122946-43-4

Literature: Strukow Zhurnal Obshchei Khimii, 1952 , vol. 22, p. 521,523; engl. Ausg. S. 587, 589

Precursor 2
541-41-3 34592-47-7
DownStream 0

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%