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6601-62-3

6601-62-3 structure
6601-62-3 structure
  • Name: Scrophulein
  • Chemical Name: cirsimaritin
  • CAS Number: 6601-62-3
  • Molecular Formula: C17H14O6
  • Molecular Weight: 314.289
  • Catalog: Natural product Flavonoids
  • Create Date: 2018-05-31 08:00:00
  • Modify Date: 2025-08-23 15:08:07
  • Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities.
Name cirsimaritin
Synonyms 5,4'-dihydroxy-6,7-dimethoxyflavone
5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxychromen-4-one
Flavone, 4',5-dihydroxy-6,7-dimethoxy-
6,7-Dimethoxyscutellarein
Circimaritin
7-Methylcapillarisin
5-Hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-4H-chromen-4-one
cirsimartin
5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-chromen-4-one
Scrophulein
4H-1-Benzopyran-4-one,5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy
Skrofulein
4H-1-Benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-6,7-dimethoxy-
4',5-Dihydroxy-6,7-dimethoxyflavone
cirsimaritin
Description Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors, with antidepressant, anxiolytic and antinociceptive activities.
Related Catalog
In Vivo Cirsimaritin significantly reduces the anxiety in mice. Cirsimaritin does not decrease by co-administration of flumazenil (2.5 mg/kg) with salvigenin, rosmanol and cirsimaritin (10 mg/kg), indicating that the high-affinity benzodiazepine binding site is not involved in the anxiolytic activity induced by these compounds[1].
References

[1]. Abdelhalim A, et al. Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis. J Pharm Pharm Sci. 2015;18(4):448-59.
Density 1.4±0.1 g/cm3
Boiling Point 563.6±50.0 °C at 760 mmHg
Molecular Formula C17H14O6
Molecular Weight 314.289
Flash Point 211.5±23.6 °C
Exact Mass 314.079041
PSA 89.13000
LogP 1.97
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.646
Storage condition ?20°C
Symbol GHS06 GHS09
GHS06, GHS09
Signal Word Danger
Hazard Statements H301-H410
Precautionary Statements P273-P301 + P310-P501
Hazard Codes T,N
Risk Phrases 25-50
Safety Phrases 45-61
RIDADR UN 2811 6.1 / PGIII
HS Code 2914509090
HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
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title: CAS No. 6601-62-3 | Chemsrc address: https://www.chemsrc.com/en/baike/525287.html

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