DC Chemicals Limited
China
Product Name: 5,7-dihydroxychromone
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5,7-Dihydroxy chromone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

31721-94-5

31721-94-5 structure

Name: 5,7-Dihydroxychromone
Chemical Name: 5,7-dihydroxychromen-4-one
CAS Number: 31721-94-5
Molecular Formula: C₉H₆O₄
Molecular Weight: 178.141
Catalog: Natural product Phenols
Create Date: 2018-07-06 17:53:11
Modify Date: 2025-08-25 03:03:31
5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1].

Name	5,7-dihydroxychromen-4-one
Synonyms	4H-1-Benzopyran-4-one, 5,7-dihydroxy- 5,7-dihydroxy-4H-1-benzopyran-4-one 5,7-Dihydroxychromone 2H-1-Benzopyran-2-one, 5,7-dihydroxy- 5,7-Dihydroxy-4H-chromen-4-one 5,7-Dihydroxy-2H-chromen-2-one 5,7-dihydroxy-chromen-4-one 5,7-Dihydroxy-chromen-4-on 5,7-DIHYDROXYCOUMARIN

Description	5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Arenavirus Signaling Pathways >> NF-κB >> Keap1-Nrf2 Signaling Pathways >> Epigenetics >> PARP Signaling Pathways >> Apoptosis >> Caspase Research Areas >> Neurological Disease Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	Nrf2 Caspase-3 Caspase-9 PARP
References	[1]. Kim DW, et al. Neuroprotection against 6-OHDA-induced oxidative stress and apoptosis in SH-SY5Y cells by 5,7-Dihydroxychromone: Activation of the Nrf2/ARE pathway. Life Sci. 2015 Jun 1;130:25-30.

Density	1.6±0.1 g/cm3
Boiling Point	399.4±42.0 °C at 760 mmHg
Melting Point	232-273℃
Molecular Formula	C₉H₆O₄
Molecular Weight	178.141
Flash Point	170.8±21.4 °C
Exact Mass	178.026611
PSA	70.67000
LogP	0.54
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.689

Hazard Codes	Xi
HS Code	2914400090

480-66-0

124-63-0

~5%

31721-94-5

Literature: Li, Su-Yi; Wang, Xiao-Bing; Xie, Sai-Sai; Jiang, Neng; Wang, Kelvin D.G.; Yao, He-Quan; Sun, Hong-Bin; Kong, Ling-Yi European Journal of Medicinal Chemistry, 2013 , vol. 69, p. 632 - 646

480-66-0

68-12-2

~93%

31721-94-5

Literature: Zheng, Shu-Yan; Li, Xiao-Ping; Tan, Hong-Sheng; Yu, Chun-Hui; Zhang, Jing-Hua; Shen, Zheng-Wu European Journal of Organic Chemistry, 2013 , # 7 p. 1356 - 1366

480-66-0

31721-94-5

Literature: Jain, A. C.; Gupta, S. M.; Tyagi, O. D. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 11 p. 1036 - 1039

546115-69-9

31721-94-5

Literature: Organic Preparations and Procedures International, , vol. 23, # 3 p. 390 - 392

89-84-9

31721-94-5

Literature: Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 28, # 5 p. 497 - 502 Khimiya Geterotsiklicheskikh Soedinenii, Sbornik, , # 5 p. 595 - 600

480-66-0

2258-42-6

31721-94-5

Literature: Jain, A. C.; Gupta, S. M.; Tyagi, O. D. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 11 p. 1036 - 1039

35811-69-9

31721-94-5

Literature: Organic Preparations and Procedures International, , vol. 23, # 3 p. 390 - 392

Precursor 7
480-66-0 124-63-0 68-12-2 546115-69-9
89-84-9 2258-42-6 35811-69-9
DownStream 3
491-80-5 480-40-0 95603-90-0

HS Code	2914400090
Summary	2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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