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AZD-6280

Names

[ CAS No. ]:
942436-93-3

[ Name ]:
AZD-6280

[Synonym ]:
unii-b9z1oeh19d
azd-6280

Biological Activity

[Description]:

AZD-6280 is a selective GABAA(α2/3) receptor modulator, used for treatment of generalized anxiety disorder.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor
Signaling Pathways >> Neuronal Signaling >> GABA Receptor
Research Areas >> Neurological Disease

[References]

[1]. Te Beek ET, et al. The effects of the nonselective benzodiazepine lorazepam and the α2 /α3 subunit-selective GABAA receptor modulators AZD7325 and AZD6280 on plasma prolactin levels. Clin Pharmacol Drug Dev. 2015 Mar;4(2):149-54. doi: 10.1002/cpdd.134. Epub 2014 Aug 28.


[Related Small Molecules]

(+)-Bicuculline | Picrotoxin | Aminooxyacetic acid hemihydrochloride | Riluzole | Baclofen | basmisanil | (R)-Baclofen | Etifoxine | Etomidate | Ginkgolide A | NS-11394 | 5alpha-Pregnan-3alpha-ol-20-one | CGP 52432 | L-655,708 | SAGE-217

Chemical & Physical Properties

[ Molecular Formula ]:
C20H22N4O3

[ Molecular Weight ]:
366.41400

[ Exact Mass ]:
366.16900

[ PSA ]:
102.85000

[ LogP ]:
4.19200

[ Storage condition ]:
2-8℃

Related Compounds

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