3-Indoleacetic acid

Names

[ CAS No. ]:
87-51-4

[ Name ]:
3-Indoleacetic acid

[Synonym ]:
1H-Indol-3-ylacetic acid
INDOLYL 3-ACETIC ACID
1H-Indole-3-acetic acid
b-Iaa
3-(Carboxymethyl)Indole
2-(1H-INDOL-3-YL)ACETIC ACID
2-(3-Indolyl)acetic acid
INDOLE3ACETICACID
3-Indolyl-acetic acid
3-Indolylacetic Acid
a-Iaa
(1H-INDOL-3-YL)ACETIC ACID
β-indoleacetic acid
1H-indol-3-acetic acid
Indole-3-aceticacid
EINECS 201-748-2
MFCD00005636
Heterauxin
(1H-indol-3-yl)-acetic acid
Noclosan
RHIZOPIN
INDOLE-3-BUTYRICACID
Indole-3-acetic acid
(INDOL-3-YL)ACETIC ACID
heteroauxin
3-Indoleacetic Acid
IAA
INDOL-3-YLACETIC ACID
alpha-indol-3-yl-aceticacid
JAA
3-INDOLEACETIC ACID,INDOLE-3-ACETIC ACID
3-INDOLE ACETIC ACID
indole-3-acetate
3-INDOLEACETICACID
1-(4-FLUOROPHENYL)ETHAN-1-ONE
T56 BMJ D1VQ
α-Indol-3-yl-acetic acid
indoleacetic acid
alpha-Indol-3-yl-acetic acid
Acetic acid, indolyl-
Gap
[3H]-Indoleacetic acid
INDOLEI-3-ACETIC ACID
INDOLEACETIC ACID,OFF-WHITE SOLID

Biological Activity

[Description]:

Indole-3-acetic acid (3-Indoleacetic acid; IAA) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division.

[Related Catalog]:

Research Areas >> Others

Biochemical Assay Reagents

Natural Products >> Saccharides and Glycosides

[Target]

Human Endogenous Metabolite

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
415.0±20.0 °C at 760 mmHg

[ Melting Point ]:
165-169 °C(lit.)

[ Molecular Formula ]:
C₁₀H₉NO₂

[ Molecular Weight ]:
175.184

[ Flash Point ]:
204.8±21.8 °C

[ Exact Mass ]:
175.063324

[ PSA ]:
53.09000

[ LogP ]:
1.43

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.694

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL3150000

CHEMICAL NAME :: 1H-Indole-3-acetic acid

CAS REGISTRY NUMBER :: 87-51-4

LAST UPDATED :: 199710

DATA ITEMS CITED :: 16

MOLECULAR FORMULA :: C10-H9-N-O2

MOLECULAR WEIGHT :: 175.20

WISWESSER LINE NOTATION :: T56 BMJ D1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2000 mg/kg/20W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumor types after systemic administration not seen spontaneously

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4500 mg/kg

SEX/DURATION :: female 7-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 450 mg/kg

SEX/DURATION :: female 7-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4500 mg/kg

SEX/DURATION :: female 7-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - Central Nervous System

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 4500 mg/kg

SEX/DURATION :: female 7-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 250 umol/L

REFERENCE :: PYTCAS Phytochemistry. An International Journal of Plant Biochemistry. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1961- Volume(issue)/page/year: 11,3135,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83421 No. of Facilities: 5 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 27 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
NL3150000

[ Packaging Group ]:
II

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

A new enabling proteomics methodology to investigate membrane associated proteins from parasitic nematodes: case study using ivermectin resistant and ivermectin susceptible isolates of Caenorhabditis elegans and Haemonchus contortus.

Vet. Parasitol. 207(3-4) , 266-75, (2015)

The mechanisms involved in anthelmintic resistance (AR) are complex but a greater understanding of AR management is essential for effective and sustainable control of parasitic helminth worms in lives...

FCA mediates thermal adaptation of stem growth by attenuating auxin action in Arabidopsis.

Nat. Commun. 5 , 5473, (2014)

Global warming is predicted to profoundly affect plant distribution and crop yield in the near future. Higher ambient temperature can influence diverse aspects of plant growth and development. In Arab...

Potential predictive plasma biomarkers for cervical cancer by 2D-DIGE proteomics and Ingenuity Pathway Analysis.

Tumour Biol. 36(3) , 1711-20, (2015)

The current methods available for screening and detecting cervical squamous cell carcinoma (CSCC) have insufficient sensitivity and specificity. As a result, many patients suffered from erroneous and ...