O-acetyl-L-serine

Names

[ Name ]:
O-acetyl-L-serine

[Synonym ]:
O-Acetyl-L-serin
O-ACETYL-L-SERINE
L-Serine,O-acetyl
serine acetate
(2S)-3-acetyloxy-2-aminopropanoic acid
O-Acetylserine

Biological Activity

[Description]:

O-Acetylserine (O-Acetyl-L-serine) is an intermediate in the biosynthesis of the amino acid cysteine in bacteria and plants.

[Related Catalog]:

Research Areas >> Others

Natural Products >> Others

[Target]

Human Endogenous Metabolite

[In Vitro]

O-acetylserine (OAS) is a central metabolite of sulfur assimilation, providing the carbon backbone for synthesis of cysteine. Sulfide generated through sulfate reduction is incorporated into OAS to form cysteine. OAS displays a signalling function leading to changes in transcript levels of a specific gene set irrespective of the sulfur status of the plant[1]. Treatment with external OAS increases sulfate transporter and adenosine 5′-phosphosulfate reductase gene expression consistent with a model of transcriptional induction by OAS[2].

[References]

[1]. Hubberten HM, et al. Additional role of O-acetylserine as a sulfur status-independent regulator during plant growth. Plant J. 2012 May;70(4):666-77.

[2]. Hopkins L, et al. O-acetylserine and the regulation of expression of genes encoding components for sulfate uptake and assimilation in potato. Plant Physiol. 2005 May;138(1):433-40.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.299g/cm3

[ Boiling Point ]:
297.7ºC at 760mmHg

[ Molecular Formula ]:
C₅H₉NO₄

[ Molecular Weight ]:
147.12900

[ Flash Point ]:
133.8ºC

[ Exact Mass ]:
147.05300

[ PSA ]:
89.62000

[ Storage condition ]:
-20°C

Safety Information

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%