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DC1-SMe

Names

[ CAS No. ]:
501666-85-9

[ Name ]:
DC1-SMe

Biological Activity

[Description]:

DC1-Sme is an antibody conjugate of phosphate prodrug of cytotoxic DNA alkylators for the targeted treatment of cancer.

[Related Catalog]:

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Research Areas >> Cancer

[References]

[1]. Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82.


[Related Small Molecules]

MC-Val-Cit-PAB-OH | Val-cit-PAB-OH | Mc-Val-Cit-PABC-PNP | Fmoc-Val-Cit-PAB-PNP | N-Succinimidyl 6-maleimidohexanoate | 6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)- | Fmoc-Val-Cit-PAB-OH | DC1 | UAA crosslinker 1

Chemical & Physical Properties

[ Molecular Formula ]:
C35H30ClN5O4S2

[ Molecular Weight ]:
684.23

[ Storage condition ]:
2-8℃

Related Compounds