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6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)-

Names

[ CAS No. ]:
32602-11-2

[ Name ]:
6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)-

[Synonym ]:
2,3-Bis(bromomethyl)-6-quinoxalinecarboxylic acid
6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)-

Biological Activity

[Description]:

6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)- is an useful linker for antibody-drug-conjugations (ADCs), extracted from [Bioorg Chem. 2012 Apr-Jun;41-42:1-5.] compound 1i.

[Related Catalog]:

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Research Areas >> Cancer

[References]

[1]. Ishikawa H, et al. Synthesis and antimicrobial activity of 2,3-bis(bromomethyl)quinoxaline derivatives. Bioorg Chem. 2012 Apr-Jun;41-42:1-5.


[Related Small Molecules]

MC-Val-Cit-PAB-OH | Val-cit-PAB-OH | Mc-Val-Cit-PABC-PNP | Fmoc-Val-Cit-PAB-PNP | N-Succinimidyl 6-maleimidohexanoate | Fmoc-Val-Cit-PAB-OH | DC1 | DC1-SMe | UAA crosslinker 1

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Boiling Point ]:
437.3±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C11H8Br2N2O2

[ Molecular Weight ]:
360.001

[ Flash Point ]:
218.3±27.3 °C

[ Exact Mass ]:
357.895233

[ LogP ]:
2.51

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.731

Related Compounds