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UAA crosslinker 1

Names

[ CAS No. ]:
1167421-25-1

[ Name ]:
UAA crosslinker 1

[Synonym ]:
(S)-2-Amino-6-((2-azidoethoxy)carbonylamino)hexanoic acid
UAA crosslinker 1

Biological Activity

[Description]:

UAA crosslinker 1 act as substrates for pylRS/tRNA pair that enable its incorporation into a target protein.

[Related Catalog]:

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Research Areas >> Cancer

[References]

[1]. VanBrunt MP, et al. Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody-Drug Conjugates Using Click Cycloaddition Chemistry. Bioconjug Chem. 2015 Nov 18;26(11):2249-60.


[Related Small Molecules]

MC-Val-Cit-PAB-OH | Val-cit-PAB-OH | Mc-Val-Cit-PABC-PNP | Fmoc-Val-Cit-PAB-PNP | N-Succinimidyl 6-maleimidohexanoate | 6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)- | Fmoc-Val-Cit-PAB-OH | DC1 | DC1-SMe

Chemical & Physical Properties

[ Molecular Formula ]:
C9H17N5O4

[ Molecular Weight ]:
259.26200

[ Exact Mass ]:
259.12800

[ PSA ]:
151.40000

[ LogP ]:
1.14906

[ Storage condition ]:
-20C

Related Compounds

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