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DC1

Names

[ CAS No. ]:
169901-27-3

[ Name ]:
DC1

Biological Activity

[Description]:

DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer.

[Related Catalog]:

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Research Areas >> Cancer

[References]

[1]. Kovtun YV, et al. Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen. Cancer Res. 2006 Mar 15;66(6):3214-21.


[Related Small Molecules]

MC-Val-Cit-PAB-OH | Val-cit-PAB-OH | Mc-Val-Cit-PABC-PNP | Fmoc-Val-Cit-PAB-PNP | N-Succinimidyl 6-maleimidohexanoate | 6-Quinoxalinecarboxylic acid, 2,3-bis(bromomethyl)- | Fmoc-Val-Cit-PAB-OH | DC1-SMe | UAA crosslinker 1

Chemical & Physical Properties

[ Molecular Formula ]:
C34H28ClN5O4S

[ Molecular Weight ]:
638.14

[ Storage condition ]:
2-8℃

Related Compounds