D-arabinitol

Names

[ CAS No. ]:
488-82-4

[ Name ]:
D-arabinitol

[Synonym ]:
MFCD00004709
(2R,4R)-pentane-1,2,3,4,5-pentol
arabinitol
EINECS 207-686-2
(+)-Arabitol
Arabitol
(2R,4R)-1,2,3,4,5-Pentanepentol
D-Arabitol
D-threo-Pentitol
D-(+)-Arabitol
D-(+)-Arabinitol

Biological Activity

[Description]:

Arabinitol, D- is a polyol and its accumulation may cause a neurotoxic effect in human.

[Related Catalog]:

Natural Products >> Saccharides and Glycosides

Research Areas >> Metabolic Disease

Research Areas >> Neurological Disease

[Target]

Human Endogenous Metabolite

[References]

[1]. Klusmann A, et al. Influence of D-arabitol and ribitol on neuronal network activity. J Inherit Metab Dis. 2005;28(6):1181-3.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
494.5±40.0 °C at 760 mmHg

[ Melting Point ]:
101-104ºC

[ Molecular Formula ]:
C₅H₁₂O₅

[ Molecular Weight ]:
152.146

[ Flash Point ]:
261.9±21.9 °C

[ Exact Mass ]:
152.068466

[ PSA ]:
101.15000

[ LogP ]:
-3.77

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.571

[ Storage condition ]:
Refrigerator (+4°C)

[ Water Solubility ]:
H2O: 0.1 g/mL, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
24/25-36-26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29054980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 29054980

Articles

A geographical discrimination of Shanxi extra aged vinegars using polyalcohols as the discriminators.

J. AOAC Int. 96(5) , 1048-53, (2013)

A discrimination method based on polyalcohol determination was developed for authenticity of protected geographical indication (PGI) vinegars-Shanxi extra aged vinegar (SVs) in China. Six polyalcohols...

High-dose diosgenin reduces bone loss in ovariectomized rats via attenuation of the RANKL/OPG ratio.

Int. J. Mol. Sci. 15(9) , 17130-47, (2014)

The aim of this study was to evaluate effect of diosgenin (DG) on rats that had osteoporosis-like features induced by ovariectomy (OVX). Seventy-two six-month-old female Wistar rats were subjected to ...

L-arabitol is the actual inducer of xylanase expression in Hypocrea jecorina (Trichoderma reesei).

Appl. Environ. Microbiol. 77 , 5988-5994, (2011)

The saprophytic fungus Hypocrea jecorina (anamorph, Trichoderma reesei) is an important native producer of hydrolytic enzymes, including xylanases. Regarding principles of sustainability, cheap and re...