3-Hydroxydodecanoic acid

Names

[ Name ]:
3-Hydroxydodecanoic acid

[Synonym ]:
(3RS)-3-hydroxydodecanoic acid
3-Hydroxydodecanoate
3-Hydroxy-laurinsaeure
b-hydroxylauric acid
3-hydroxy-dodecanoic acid
3-Hydroxy-dodecansaeure
3-Hydroxydodecanoic acid
Dodecanoic acid,3-hydroxy

Biological Activity

[Description]:

3-Hydroxydodecanoic acid is a medium-chain fatty acid associated with fatty acid metabolic disorders.

[Related Catalog]:

Natural Products >> Acids and Aldehydes

Research Areas >> Others

[Target]

Human Endogenous Metabolite

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
0.987 g/cm3

[ Boiling Point ]:
348ºC at 760 mmHg

[ Molecular Formula ]:
C₁₂H₂₄O₃

[ Molecular Weight ]:
216.31700

[ Flash Point ]:
178.4ºC

[ Exact Mass ]:
216.17300

[ PSA ]:
57.53000

[ LogP ]:
2.96270

[ Vapour Pressure ]:
5.86E-10mmHg at 25°C

[ Index of Refraction ]:
1.576

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918199090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Analysis of polyhydroxyalkanoate (PHA) synthase gene and PHA-producing bacteria in activated sludge that produces PHA containing 3-hydroxydodecanoate.

FEMS Microbiol. Lett. 346(1) , 56-64, (2013)

Activated sludge is an alternative to pure cultures for polyhydroxyalkanoate (PHA) production due to the presence of many PHA-producing bacteria in activated sludge community. In this study, activated...

Determination of monomeric composition in polyhydroxyalkanoates by liquid chromatography coupled with on-line mass spectrometry and off-line nuclear magnetic resonance.

Talanta 146 , 107-13, (2015)

Polyhydroxyalkanoates (PHAs) are commercially-valuable biocompatible and biodegradable polymers with many potential medical, pharmaceutical and other industrial applications. The analysis of PHA monom...

Mitochondrial bioenergetics deregulation caused by long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficiencies in rat brain: a possible role of mPTP opening as a pathomechanism in these disorders?

Biochim. Biophys. Acta 1842(9) , 1658-67, (2014)

Long-chain 3-hydroxylated fatty acids (LCHFA) accumulate in long-chain 3-hydroxy-acyl-CoA dehydrogenase (LCHAD) and mitochondrial trifunctional protein (MTP) deficiencies. Affected patients usually pr...

Related Compounds

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