3-Hydroxydodecanoic acid
3-Hydroxydodecanoic acid structure
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Common Name | 3-Hydroxydodecanoic acid | ||
|---|---|---|---|---|
| CAS Number | 1883-13-2 | Molecular Weight | 216.31700 | |
| Density | 0.987 g/cm3 | Boiling Point | 348ºC at 760 mmHg | |
| Molecular Formula | C12H24O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 178.4ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Analysis of polyhydroxyalkanoate (PHA) synthase gene and PHA-producing bacteria in activated sludge that produces PHA containing 3-hydroxydodecanoate.
FEMS Microbiol. Lett. 346(1) , 56-64, (2013) Activated sludge is an alternative to pure cultures for polyhydroxyalkanoate (PHA) production due to the presence of many PHA-producing bacteria in activated sludge community. In this study, activated sludge was submitted to aerobic dynamic feeding in a seque... |
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Determination of monomeric composition in polyhydroxyalkanoates by liquid chromatography coupled with on-line mass spectrometry and off-line nuclear magnetic resonance.
Talanta 146 , 107-13, (2015) Polyhydroxyalkanoates (PHAs) are commercially-valuable biocompatible and biodegradable polymers with many potential medical, pharmaceutical and other industrial applications. The analysis of PHA monomeric composition is especially challenging due to the broad... |
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Mitochondrial bioenergetics deregulation caused by long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficiencies in rat brain: a possible role of mPTP opening as a pathomechanism in these disorders?
Biochim. Biophys. Acta 1842(9) , 1658-67, (2014) Long-chain 3-hydroxylated fatty acids (LCHFA) accumulate in long-chain 3-hydroxy-acyl-CoA dehydrogenase (LCHAD) and mitochondrial trifunctional protein (MTP) deficiencies. Affected patients usually present severe neonatal symptoms involving cardiac and hepati... |
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Analysis of 3-hydroxydodecanedioic acid for studies of fatty acid metabolic disorders: preparation of stable isotope standards.
J. Clin. Lab Anal. 16(2) , 115-20, (2002) Current diagnostic tests to detect disorders of fatty acids metabolism, such as long-chain hydroxyacyl CoA dehydrogenase deficiency (LCHAD), are hampered by insensitivity or a long delay time required for results. Children with LCHAD deficiency are known to e... |
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Production of polyhydroxyalkanoates with high 3-hydroxydodecanoate monomer content by fadB and fadA knockout mutant of Pseudomonas putida KT2442.
Biomacromolecules 8 , 2504-2511, (2007) Pseudomonas putida KT2442 produces medium-chain-length (MCL) polyhydroxyalkanoates (PHA) consisting of 3-hydroxyhexanoate (HHx), 3-hydroxyoctanoate (HO), 3-hydroxydecanoate (HD), and 3-hydroxydodecanoate (HDD) from a wide-range of carbon sources. In this stud... |
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The Burkholderia cenocepacia BDSF quorum sensing fatty acid is synthesized by a bifunctional crotonase homologue having both dehydratase and thioesterase activities.
Mol. Microbiol. 83 , 840-855, (2012) Signal molecules of the diffusible signal factor (DSF) family have been shown recently to be involved in regulation of pathogenesis and biofilm formation in diverse Gram-negative bacteria. DSF signals are reported to be active not only on their cognate bacter... |
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Microbial production of 3-hydroxydodecanoic acid by pha operon and fadBA knockout mutant of Pseudomonas putida KT2442 harboring tesB gene.
Appl. Microbiol. Biotechnol. 83 , 513-519, (2009) To produce extracellular chiral 3-hydroxyacyl acids (3HA) by fermentation, a novel pathway was constructed by expressing tesB gene encoding thioesterase II into Pseudomonas putida KTOY01, which was a polyhydroxyalkanoate (PHA) synthesis operon knockout mutant... |
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The evaluation of the role of beta-hydroxy fatty acids on chronic inflammation and insulin resistance.
Mediators Inflamm. 2006 , 64980, (2006) Beta-hydroxy fatty acids are a major component of lipid A moiety of lipopolysaccharide. We aimed to investigate the role of free beta-hydroxy fatty acids on inflammation, as well as to evaluate their effects on cytokine release from human blood cells, and whe... |
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[Analysis of the impurity of bacterium source of standard endotoxin by gas chromatography/mass spectrometry].
Se Pu 24(1) , 10-3, (2006) To analyse the impurity of bacterium source of standard endotoxin, 3-hydroxy fatty acid species in different endotoxin standards was determined by gas chromatography/mass spectrometry (GC/MS) using N, O-bis (trimethylsilyl) trifluoroacetamide as the silanizin... |
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Identification, isolation, and structural studies of the outer membrane lipopolysaccharide of Caulobacter crescentus.
J. Bacteriol. 174(23) , 7595-605, (1992) The lipopolysaccharide (LPS) of the outer membrane of Caulobacter crescentus was purified and analyzed. Two distinct strains of the species, NA 1000 and CB2A, were examined; despite differences in other membrane-related polysaccharides, the two gave similar L... |