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L-2-Hydroxyglutaric acid

Names

[ CAS No. ]:
13095-48-2

[ Name ]:
L-2-Hydroxyglutaric acid

[Synonym ]:
L-2-hydroxyglutaric disodium salt
(S)-2-Hydroxy-glutarsaeure
(2S)-hydroxyglutaric acid
(2S)-2-Hydroxyglutaric Acid
(S)-2-hydroxy-glutaric acid
L-hydroxyglutaric acid
[3H]-L-2-Hydroxyglutarate
L-2-Hydroxyglutaric acid

Biological Activity

[Description]:

L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer.

[Related Catalog]:

Natural Products >> Acids and Aldehydes
Research Areas >> Cancer

[Target]

Human Endogenous Metabolite


[References]

[1]. Shim EH, et al. L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer. Cancer Discov. 2014 Nov;4(11):1290-8.


[Related Small Molecules]

3-Methyladenine | Hydrocortisone | Acetylcysteine(N-acetylcysteine) | Retinoic acid | Melatonine | Dinoprostone | Nicotinamide | Adenosine triphosphate | 4-Acetamidophenol | Prostaglandin E1 | Dehydroepiandrosterone | Corticosterone | Progesterone | Docosahexaenoic Acid | NAD+

Chemical & Physical Properties

[ Density]:
1.508g/cm3

[ Boiling Point ]:
394.2ºC at 760mmHg

[ Molecular Formula ]:
C5H8O5

[ Molecular Weight ]:
148.11400

[ Flash Point ]:
206.4ºC

[ Exact Mass ]:
148.03700

[ PSA ]:
94.83000

[ Vapour Pressure ]:
7.55E-08mmHg at 25°C

[ Index of Refraction ]:
1.519

Safety Information

[ HS Code ]:
2918199090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2918199090

[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Related Compounds