L-2-Hydroxyglutaric acid

Modify Date: 2024-01-03 18:02:45

L-2-Hydroxyglutaric acid Structure
L-2-Hydroxyglutaric acid structure
Common Name L-2-Hydroxyglutaric acid
CAS Number 13095-48-2 Molecular Weight 148.11400
Density 1.508g/cm3 Boiling Point 394.2ºC at 760mmHg
Molecular Formula C5H8O5 Melting Point N/A
MSDS N/A Flash Point 206.4ºC

 Use of L-2-Hydroxyglutaric acid


L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer.

 Names

Name (2S)-2-hydroxypentanedioic acid
Synonym More Synonyms

 L-2-Hydroxyglutaric acid Biological Activity

Description L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Shim EH, et al. L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer. Cancer Discov. 2014 Nov;4(11):1290-8.

 Chemical & Physical Properties

Density 1.508g/cm3
Boiling Point 394.2ºC at 760mmHg
Molecular Formula C5H8O5
Molecular Weight 148.11400
Flash Point 206.4ºC
Exact Mass 148.03700
PSA 94.83000
Vapour Pressure 7.55E-08mmHg at 25°C
Index of Refraction 1.519

 Safety Information

HS Code 2918199090

 Synthetic Route

~72%

L-2-Hydroxyglutaric acid Structure

L-2-Hydroxyglut...

CAS#:13095-48-2

Literature: Figadere; Franck; Cave Tetrahedron Letters, 1995 , vol. 36, # 10 p. 1637 - 1640

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L-2-Hydroxyglutaric acid Structure

L-2-Hydroxyglut...

CAS#:13095-48-2

Literature: Rustoy, Eduardo M.; Pereyra, Elba N.; Moreno, Silvia; Baldessari, Alicia Tetrahedron Asymmetry, 2004 , vol. 15, # 23 p. 3763 - 3768

~%

L-2-Hydroxyglutaric acid Structure

L-2-Hydroxyglut...

CAS#:13095-48-2

Literature: Rustoy, Eduardo M.; Pereyra, Elba N.; Moreno, Silvia; Baldessari, Alicia Tetrahedron Asymmetry, 2004 , vol. 15, # 23 p. 3763 - 3768

~%

L-2-Hydroxyglutaric acid Structure

L-2-Hydroxyglut...

CAS#:13095-48-2

Literature: Fischer,E.; Moreschi Chemische Berichte, 1912 , vol. 45, p. 2449

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L-2-Hydroxyglutaric acid Structure

L-2-Hydroxyglut...

CAS#:13095-48-2

Literature: Rustoy, Eduardo M.; Pereyra, Elba N.; Moreno, Silvia; Baldessari, Alicia Tetrahedron Asymmetry, 2004 , vol. 15, # 23 p. 3763 - 3768

~%

L-2-Hydroxyglutaric acid Structure

L-2-Hydroxyglut...

CAS#:13095-48-2

Literature: Rustoy, Eduardo M.; Pereyra, Elba N.; Moreno, Silvia; Baldessari, Alicia Tetrahedron Asymmetry, 2004 , vol. 15, # 23 p. 3763 - 3768

~%

L-2-Hydroxyglutaric acid Structure

L-2-Hydroxyglut...

CAS#:13095-48-2

Literature: Rustoy, Eduardo M.; Pereyra, Elba N.; Moreno, Silvia; Baldessari, Alicia Tetrahedron Asymmetry, 2004 , vol. 15, # 23 p. 3763 - 3768

~%

L-2-Hydroxyglutaric acid Structure

L-2-Hydroxyglut...

CAS#:13095-48-2

Literature: Weil-Malherbe Biochemical Journal, 1937 , vol. 31, p. 2206

 Customs

HS Code 2918199090
Summary 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Synonyms

L-2-hydroxyglutaric disodium salt
(S)-2-Hydroxy-glutarsaeure
(2S)-hydroxyglutaric acid
(2S)-2-Hydroxyglutaric Acid
(S)-2-hydroxy-glutaric acid
L-hydroxyglutaric acid
[3H]-L-2-Hydroxyglutarate
L-2-Hydroxyglutaric acid