<Suppliers Price>

PF-4778574

Names

[ CAS No. ]:
1219633-99-4

[ Name ]:
PF-4778574

Biological Activity

[Description]:

PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Signaling Pathways >> Neuronal Signaling >> iGluR
Research Areas >> Neurological Disease

[Target]

EC50: 45 to 919 nM (AMPAR)[1]


[References]

[1]. Shaffer, C.L.; Scialis, R.J.; Lotarski, S.; et al. Defining themechanism-mediated exposure-response continuum of a novelAMPA receptor potentiator. 39th Annu Meet Soc Neurosci (October17-21, Chicago) 2009, Abst 883.17


[Related Small Molecules]

(+)-MK 801 Maleate | CNQX | N-Methyl-D-aspartic acid | ifenprodil tartrate | D-AP5(mM/ml) | DNQX | Ro 25-6981 maleate | Flupirtine maleate | Mibampator | CX546 | Naspm | Talampanel | Centrophenoxine hydrochloride | 24-Hydroxycholesterol

Chemical & Physical Properties

[ Molecular Formula ]:
C19H22N2O3S2

[ Molecular Weight ]:
390.52000

[ Exact Mass ]:
390.10700

[ PSA ]:
115.81000

[ LogP ]:
4.95878

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.