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L-Homocitrulline

Names

[ CAS No. ]:
1190-49-4

[ Name ]:
L-Homocitrulline

[Synonym ]:
Lysine, N-(aminocarbonyl)-
EINECS 214-722-0
L-HOMOCITRULLINE
2-Amino-6-(carbamoylamino)hexanoic acid
MFCD00038143
N-Carbamoyllysine
N6-carbamoyl-Lysine

Biological Activity

[Description]:

L-Homocitrulline is metabolized to homoarginine through homoargininosuccinate via the urea cycle pathway and its metabolic abnormality could lead to Lysinuric Protein Intolerance (LPI).

[Related Catalog]:

Research Areas >> Metabolic Disease
Natural Products >> Others

[Target]

Human Endogenous Metabolite


[References]

[1]. Kato T, et al. Homocitrullinuria and homoargininuria in lysinuric protein intolerance. J Inherit Metab Dis. 1989;12(2):157-61.


[Related Small Molecules]

3-Methyladenine | Hydrocortisone | Acetylcysteine(N-acetylcysteine) | Retinoic acid | Melatonine | Dinoprostone | Nicotinamide | Adenosine triphosphate | 4-Acetamidophenol | Prostaglandin E1 | Dehydroepiandrosterone | Corticosterone | Progesterone | Docosahexaenoic Acid | NAD+

Chemical & Physical Properties

[ Density]:
1.241±0.06 g/cm3

[ Boiling Point ]:
393.0±42.0 °C at 760 mmHg

[ Melting Point ]:
211-212 ºC (decomp)

[ Molecular Formula ]:
C7H15N3O3

[ Molecular Weight ]:
189.212

[ Flash Point ]:
191.5±27.9 °C

[ Exact Mass ]:
189.111343

[ PSA ]:
118.44000

[ LogP ]:
-1.60

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.525

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Soluble (49 g/L) (25 ºC)

MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36/37/39

[ WGK Germany ]:
3

[ HS Code ]:
2924199090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%


Related Compounds

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