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Naspm (trihydrochloride)

Names

[ CAS No. ]:
1049731-36-3

[ Name ]:
Naspm (trihydrochloride)

[Synonym ]:
1-Naphthylacetyl Spermine Trihydrochloride
Naspm (trihydrochloride)

Biological Activity

[Description]:

Naspm (1-Naphthyl acetyl spermine) trihydrochloride, a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Signaling Pathways >> Neuronal Signaling >> iGluR
Research Areas >> Neurological Disease

[References]

[1]. Koike M, et al. Blocking effect of 1-naphthyl acetyl spermine on Ca2+-permeable AMPA receptors in cultured rat hippocampal neurons. Neurosci Res. 1997 Sep;29(1):27-36.


[Related Small Molecules]

(+)-MK 801 Maleate | CNQX | N-Methyl-D-aspartic acid | ifenprodil tartrate | D-AP5(mM/ml) | DNQX | Ro 25-6981 maleate | Flupirtine maleate | Mibampator | CX546 | Naspm | Talampanel | Centrophenoxine hydrochloride | 24-Hydroxycholesterol

Chemical & Physical Properties

[ Molecular Formula ]:
C22H37Cl3N4O

[ Molecular Weight ]:
479.91400

[ Exact Mass ]:
478.20300

[ PSA ]:
82.67000

[ LogP ]:
6.92520

[ Storage condition ]:
2-8℃

Related Compounds

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