1049731-36-3

1049731-36-3 structure

Name: Naspm (trihydrochloride)
Chemical Name: N-[3-({4-[(3-Aminopropyl)amino]butyl}amino)propyl]-2-(1-naphthyl) acetamide trihydrochloride
CAS Number: 1049731-36-3
Molecular Formula: C₂₂H₃₇Cl₃N₄O
Molecular Weight: 479.91400
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2016-03-16 06:07:55
Modify Date: 2025-08-25 18:06:36
Naspm (1-Naphthyl acetyl spermine) trihydrochloride, a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.

Name	N-[3-({4-[(3-Aminopropyl)amino]butyl}amino)propyl]-2-(1-naphthyl) acetamide trihydrochloride
Synonyms	1-Naphthylacetyl Spermine Trihydrochloride Naspm (trihydrochloride)

Description	Naspm (1-Naphthyl acetyl spermine) trihydrochloride, a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease
References	[1]. Koike M, et al. Blocking effect of 1-naphthyl acetyl spermine on Ca2+-permeable AMPA receptors in cultured rat hippocampal neurons. Neurosci Res. 1997 Sep;29(1):27-36.