MurA-IN-2

Modify Date: 2023-05-28 13:34:21

MurA-IN-2 structure	Common Name	MurA-IN-2
	CAS Number	2164447-18-9	Molecular Weight	229.75
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₂₀ClNO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MurA-IN-2

MurA-IN-2 (compound 37), a chloroacetamide fragment containing a primary aliphatic amine, is a potent MurA inhibitor with an IC50 value of 39  μM. MurA-IN-2 has antibacterial activity and inhibits the bacterial cell wall synthesis[1].

Name	MurA-IN-2

Description	MurA-IN-2 (compound 37), a chloroacetamide fragment containing a primary aliphatic amine, is a potent MurA inhibitor with an IC50 value of 39  μM. MurA-IN-2 has antibacterial activity and inhibits the bacterial cell wall synthesis[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 39 μM (MurA)[1]
In Vitro	MurA-IN-2 (compound 37; 128 μg/mL) inhibits bacteria S. aureus ATCC29213 and E. coli ATCC25922 activity[1].
References	[1]. Grabrijan K, et, al. Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead. Eur J Med Chem. 2022 Sep 13; 114752. [2]. Grabrijan K, et, al. Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead. Eur J Med Chem. 2022 Sep 13; 114752.

Molecular Formula	C₁₂H₂₀ClNO
Molecular Weight	229.75

MurA-IN-2

Use of MurA-IN-2

Names

MurA-IN-2 Biological Activity

Chemical & Physical Properties