354815-90-0
354815-90-0 structure
- Name: MurA-IN-1
- Chemical Name: 3a,4,5,9b-tetrahydro-3h-cyclopenta[c]quinoline-4-carboxylic acid
- CAS Number: 354815-90-0
- Molecular Formula: C13H13NO2
- Molecular Weight: 215.25
- Catalog: Research Areas Others
- Create Date: 2019-02-17 19:08:26
- Modify Date: 2025-08-21 16:04:56
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MurA-IN-1 (compound 1a) is a PTPRR inhibitor, with IC50 values of 0.23 μM, 0.8 μM, 0.75 μM and 0.09 μM for PTP1B, PTPN5, PTPN7 and PTPRR, respectively[1]. (A family of human MAPK-specific protein tyrosine phosphatases)
| Name | 3a,4,5,9b-tetrahydro-3h-cyclopenta[c]quinoline-4-carboxylic acid |
|---|
| Description | MurA-IN-1 (compound 1a) is a PTPRR inhibitor, with IC50 values of 0.23 μM, 0.8 μM, 0.75 μM and 0.09 μM for PTP1B, PTPN5, PTPN7 and PTPRR, respectively[1]. (A family of human MAPK-specific protein tyrosine phosphatases) |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.23 μM (PTP1B), 0.8 μM (PTPN5), 0.75 μM (PTPN7), 0.09 μM (PTPRR)[1]. |
| References |
| Density | 1.25g/cm3 |
|---|---|
| Boiling Point | 406.5ºC at 760 mmHg |
| Molecular Formula | C13H13NO2 |
| Molecular Weight | 215.25 |
| Flash Point | 199.7ºC |
| Exact Mass | 215.09500 |
| PSA | 49.33000 |
| LogP | 2.36300 |
| Index of Refraction | 1.606 |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Hazard Codes | Xi |
| RIDADR | UN 2811 6.1 / PGIII |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |