ARTD10/PARP10-IN-2

Modify Date: 2024-05-01 22:12:30

ARTD10/PARP10-IN-2 structure	Common Name	ARTD10/PARP10-IN-2
	CAS Number	1708103-69-8	Molecular Weight	247.25
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₂H₁₃N₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ARTD10/PARP10-IN-2

ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1 with IC50s of 2.0 μM, and 9.7 μM, respectively[1].

Name	ARTD10/PARP10-IN-2

Description	ARTD10/PARP10-IN-2 (compound 19) is a potent and non-selective PARP inhibitor, targeting to mono-ADP-ribosyltransferases ARTD10/PARP10 and poly(ADP-ribose) polymerase-1 ARTD1/PARP1 with IC50s of 2.0 μM, and 9.7 μM, respectively[1].
Related Catalog	Signaling Pathways >> Epigenetics >> PARP Research Areas >> Inflammation/Immunology Signaling Pathways >> Cell Cycle/DNA Damage >> PARP
Target	ARTD1/PARP1:9.7 μM (IC50) ARTD10/PARP10:2.0 μM (IC50) ARTD8/PARP14:>20 μM (IC50) ARTD7/PARP15:>20 μM (IC50)
References	[1]. Ekblad T, et al. Towards small molecule inhibitors of mono-ADP-ribosyltransferases. Eur J Med Chem. 2015 May 5;95:546-51.

Molecular Formula	C₁₂H₁₃N₃O₃
Molecular Weight	247.25

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ARTD10/PARP10-IN-2

Use of ARTD10/PARP10-IN-2

Names

ARTD10/PARP10-IN-2 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.