DL-Homocysteine
DL-Homocysteine structure
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Common Name | DL-Homocysteine | ||
|---|---|---|---|---|
| CAS Number | 6027-13-0 | Molecular Weight | 135.185 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 299.7±35.0 °C at 760 mmHg | |
| Molecular Formula | C4H9NO2S | Melting Point | 231 °C | |
| MSDS | Chinese USA | Flash Point | 135.0±25.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of DL-HomocysteineL-Homocysteine, a homocysteine metabolite, is a homocysteine that has L configuration. L-Homocysteine induces upregulation of cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia[1][2]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | L-homocysteine |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | L-Homocysteine, a homocysteine metabolite, is a homocysteine that has L configuration. L-Homocysteine induces upregulation of cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
[1]. Finkelstein JD, et al. Homocysteine. Int J Biochem Cell Biol. 2000 Apr;32(4):385-9. |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 299.7±35.0 °C at 760 mmHg |
| Melting Point | 231 °C |
| Molecular Formula | C4H9NO2S |
| Molecular Weight | 135.185 |
| Flash Point | 135.0±25.9 °C |
| Exact Mass | 135.035400 |
| PSA | 102.12000 |
| LogP | 0.22 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.538 |
| InChIKey | FFFHZYDWPBMWHY-VKHMYHEASA-N |
| SMILES | NC(CCS)C(=O)O |
| Storage condition | ?20°C |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 10 | |
|---|---|
| DownStream 10 | |
CAS#:63-68-3
CAS#:31828-68-9
CAS#:626-72-2
CAS#:147331-83-7
CAS#:2338-04-7
CAS#:69955-57-3
CAS#:7689-60-3
CAS#:7540-67-2
CAS#:70-18-8
CAS#:75027-08-6
CAS#:56-88-2
CAS#:7732-18-5
CAS#:7783-06-4
CAS#:52-90-4
CAS#:1118-68-9
CAS#:979-92-0This table lists relevant public references with title, journal and publication metadata for this compound.
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Biomarkers of one-carbon metabolism are associated with biomarkers of inflammation in women.
J. Nutr. 144(5) , 714-21, (2014) Folate-mediated one-carbon metabolism is essential for DNA synthesis, repair, and methylation. Perturbations in one-carbon metabolism have been implicated in increased risk of some cancers and may als... |
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Abstracts of the 9th International Conference On Homocysteine and One-Carbon Metabolism - HCY2013. Dublin, Ireland. September 8-12, 2013.
J. Inherit. Metab. Dis. 36 Suppl 1 , S1-54, (2013)
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Derivation and validation of homocysteine score in u.s. Men and women.
J. Nutr. 145(1) , 96-104, (2015) One-carbon metabolism, which is crucial in DNA synthesis and genomic stability, is an interrelated network of biochemical reactions involved in several dietary and lifestyle factors. The development o... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| (2S)-2-amino-4-sulfanylbutanoic acid |
| L-2-Amino-4-Mercapto-butyric acid |
| (S)-2-amino-4-mercapto-Butanoic acid |
| DL-2-amino-4-mercapto-Butyric acid |
| HOMO-CYS |
| H-Hcys-OH |
| DL-2-Amino-4-mercaptobutyric acid |
| (S)-2-Amino-4-mercaptobutanoic acid |
| 2-Amino-4-mercaptobutyric acid |
| D,L-Homocysteine |
| (S)-homocysteine |
| MFCD00151320 |
| 2-amino-4-mercapto-DL-Butyric acid |
| 2-amino-4-sulfanylbutanoic acid |
| EINECS 227-891-0 |
| D,L-homocystine |
| Homocysteine (VAN) |
| 2-Amino-4-Mercapto-Butyric Acid |
| (S)-2-Amino-4-mercaptobutyric acid |
| (±)-Homocysteine |
| 2-amino-4-mercapto-Butanoic acid |
| UNII:S7IJP4A89K |
| Homocysteine |
| Butyric acid, 2-amino-4-mercapto-, DL- (9CI) |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the InChIKey of L-homocysteine? |
| A: InChIKey of L-homocysteine is FFFHZYDWPBMWHY-VKHMYHEASA-N. |
| Q: What is the LogP of L-homocysteine? |
| A: LogP of L-homocysteine is 0.22. |
| Q: What is the polar surface area (PSA) of L-homocysteine? |
| A: Polar surface area (PSA) of L-homocysteine is 102.12000. |
| Q: What are the downstream products of L-homocysteine? |
| A: Related downstream products(CAS) of L-homocysteine: 56-88-2;7732-18-5;7783-06-4;52-90-4;70-18-8;75027-08-6;626-72-2;63-68-3;1118-68-9;979-92-0. |
| Q: What is the boiling point of L-homocysteine? |
| A: Boiling point of L-homocysteine is 299.7±35.0 °C at 760 mmHg. |
| Q: What is the molecular formula of L-homocysteine? |
| A: Molecular formula of L-homocysteine is C4H9NO2S. |
| Q: What is the melting point of L-homocysteine? |
| A: Melting point of L-homocysteine is 231 °C. |
| Q: What is the CAS number of L-homocysteine? |
| A: CAS number of L-homocysteine is 6027-13-0. |
| Q: What is the English name of L-homocysteine? |
| A: The English name of L-homocysteine is L-homocysteine. |
| Q: What are the storage conditions for L-homocysteine? |
| A: Storage conditions for L-homocysteine: ?20°C. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |