Chemistry–An Asian Journal

Microwave??Accelerated Pd??Catalyzed Desulfitative Direct C2??Arylation of Free (NH)??Indoles with Arylsulfinic Acids

T Miao, P Li, GW Wang, L Wang

Index: Miao, Tao; Li, Pinhua; Wang, Guan-Wu; Wang, Lei Chemistry - An Asian Journal, 2013 , vol. 8, # 12 p. 3185 - 3190

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Citation Number: 29

Abstract

Abstract The rapid and efficient direct C2-arylation of free (NH)-indoles with arylsulfinic acids proceeded through a microwave-accelerated palladium-catalyzed desulfitation reaction. By using PdCl 2 as a catalyst, silver acetate as an oxidant, and H 2 SO 4 as an additive, arylsulfinic acids with both electron-donating and electron-withdrawing groups underwent desulfitative coupling with an array of free (NH)-indoles, thereby selectively providing C2- ...

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