e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Rifamycins. 1 XXXV. 2 Amides and Hydrazides of Rifamycin B3

P Sensi, N Maggi, R Ballotta, S Fürész…

Index: Sensi,P. et al. Journal of Medicinal Chemistry, 1964 , vol. 7, p. 596 - 602

Full Text: HTML

Citation Number: 33

Abstract

63 C4, HjgSU013 65, 72 6.81 3.26 64.80 7.01 3.55 84 CnHj, SgOir 65.72 6.81 3.26 65.14 7.39 3.71 17 C4jHjgs~ C) la 63.66 6.65 3.30 62.61 7.13 3.34 26 C43H&. 1014 62.45 7.07 3.39 61.60 7.40 3.06 20 C;, H [IN; O;; 63.37 6.65 5.04 62.62 7.40 4.60 36 C* H, CH; CH, S (C~ H,), 64 C;; H;, SiO;; 63.99 7.66 4.76 63.00 7.88 4.44 37 CH3(CH,) 2X (CH,), S (C? Hj) 2 30 CjOHj4K401a 63.94 7.94 5. 97 63.95 8.2% 5.65

Piperidine Structure

rifamycin B Structure

~%

Rifamycin B piperidide Structure

Rifamycin B pip...

2-(1-methyl-1H-pyridin-2-ylidene)-N-phenyl-thioacetamide Structure

2-(1-methyl-1H-...

rifamycin B Structure

~%

Rifamycin B dibutylethylhydrazide Structure

Rifamycin B dib...

3,5-Dimethylmorpholine Structure

3,5-Dimethylmor...

rifamycin B Structure

~%

4-O-[2-(3,5-Dimethyl-4-morpholinyl)-2-oxoethyl]rifamycin Structure

4-O-[2-(3,5-Dim...

N/A Structure

rifamycin B Structure

~%

Acetic acid, [[1,2-dihydro-5,6,17,19,21-pentahydroxy-23-methoxy-2, 4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca[1,11, 13]trienimino)naphtho[2,1-b]furan-9-yl]oxy]-, 21-acetate, 2, 2-dipr Structure

Acetic acid, [[...

N-Methylbutylamine Structure

N-Methylbutylamine

rifamycin B Structure

~%

Rifamycin,4-O-[2-(butylmethylamino)-2-oxoethyl]- (9CI) Structure

Rifamycin,4-O-[...

rifamycin B Structure

Diallylamine Structure

~%

Acetamide, 2-((1,2-dihydro-5,6,17,19,21-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-9-yl)oxy)-N,N-diallyl-, 21-acetate Structure

Acetamide, 2-((...

N-Ethyl-1-propanamine Structure

N-Ethyl-1-propa...

rifamycin B Structure

~%

Rifamycin B ethylpropylamide Structure

Rifamycin B eth...

1,1,2-Tripropylhydrazine Structure

1,1,2-Tripropyl...

rifamycin B Structure

~%

Rifamycin, 4-O-[2-oxo-2- (tripropylhydrazino)ethyl]- Structure

Rifamycin, 4-O-...

methyl-morpholin-4-yl-amine Structure

methyl-morpholi...

rifamycin B Structure

~%

4-O-[2-(Methylmorpholinoamino)-2-oxoethyl]rifamycin Structure

4-O-[2-(Methylm...

3-Methylmorpholine Structure

3-Methylmorpholine

rifamycin B Structure

~%

Rifamycin B methylmorpholide Structure

Rifamycin B met...

rifamycin B Structure

tert-Butylamine Structure

tert-Butylamine

~%

O4-(tert-butylcarbamoyl-methyl)-rifamycin Structure

O4-(tert-butylc...

rifamycin B Structure

Diethylamine Structure

~%

rifamide Structure

1,1-dimethyl-2-pentylhydrazine Structure

1,1-dimethyl-2-...

rifamycin B Structure

~%

Acetic acid, [[1,2-dihydro-5,6,17,19,21-pentahydroxy-23-methoxy-2, 4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca[1,11, 13]trienimino)naphtho[2,1-b]furan-9-yl]oxy]-, 21-acetate, 2, 2-dime Structure

Acetic acid, [[...

1,1-diethyl-2-propylhydrazine Structure

1,1-diethyl-2-p...

rifamycin B Structure

~%

Acetic acid, ((1,2-dihydro-5,6,17,19,21-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-9-yl)oxy)-, 21-acetate, 2,2-diethyl Structure

Acetic acid, ((...

N-(1-Propyl)propargylamine Structure

N-(1-Propyl)pro...

rifamycin B Structure

~%

l acetate Structure

N-Ethylaniline Structure

rifamycin B Structure

~%

Rifamycin,4-O-[2-(ethylphenylamino)-2-oxoethyl]- (9CI) Structure

Rifamycin,4-O-[...

2,5-Dimethylpyrrolidine Structure

2,5-Dimethylpyr...

rifamycin B Structure

~%

O4-[2-((2ξ)-2r,5ξ-dimethyl-pyrrolidin-1-yl)-2-oxo-ethyl]-rifamycin Structure

O4-[2-((2ξ)-2r,...

(diethylamino)ethylamine Structure

(diethylamino)e...

rifamycin B Structure

~%

Acetic acid, [[1,2-dihydro-5,6,17,19,21-pentahydroxy-23-methoxy-2, 4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca[1,11, 13]trienimino)naphtho[2,1-b]furan-9-yl]oxy]-, 21-acetate, 1,2, 2-tr Structure

Acetic acid, [[...

Ethylamine Structure

rifamycin B Structure

~%

Rifamycin B ethylamide Structure

Rifamycin B eth...

N'-methyl-N,N-dipropyl-hydrazine Structure

N'-methyl-N,N-d...

rifamycin B Structure

~%

Rifamycin, 4-O-(2-(1-methyl-2,2-dipropylhydrazino)-2-oxoethyl)- (9CI) Structure

Rifamycin, 4-O-...

Diisobutylamine Structure

Diisobutylamine

rifamycin B Structure

~%

Rifamycin,4-O-[2-[bis(2-methylpropyl)amino]-2-oxoethyl]- (9CI) Structure

Rifamycin,4-O-[...

Methyl-n-propylamine Structure

Methyl-n-propylamine

rifamycin B Structure

~%

4-O-[2-(Methylpropylamino)-2-oxoethyl]rifamycin Structure

4-O-[2-(Methylp...

N/A Structure

rifamycin B Structure

~%

Rifamycin B, 2,2-diethyl-1-methylhydrazide Structure

Rifamycin B, 2,...