A pyrimidine compound refers to a six-membered heterocyclic compound having two nitrogen atoms in its molecular structure, and is an isomer with pyridazine and pyrazine. There is a special ultraviolet spectrum due to the presence of conjugated double bonds in the molecular structure. Soluble in water, its basicity is weaker than pyridine, it is difficult to undergo electrophilic substitution reaction, only bromination reaction can occur in the 5-position, nitrification and sulfonation reaction can not occur, but nucleophilic substitution and pyrimidine derivation are more likely to occur. It is widely found in nature, such as sulfadiazine, barbital, vitamin B1 and so on. In nucleic acids, there are three important pyrimidine bases, which are uracil, thymine, and cytosine. They mainly contain cytosine and thymine in DNA, and mainly contain cytosine and uracil in RNA. It also contains a small number of pyrimidine modified bases. Many drugs (such as sulfadiazine, trimethoprim, 6-mercaptopurine) contain a pyrimidine ring. Widely used as pharmaceutical raw materials, such as vitamin B, sulfadiazine, sulfamethoxazole, sulfamonomethoxine; pesticide raw materials, such as diazinon, pyrimidinol, chlorfenapyr, herbicide, pyridine, rat Dead, cyclosporine, belfamicin, acetaminophen, sulfamethoxazole, bisazinone, anti-carbocarb, ethyl chlorpyrifos, chlorpyrifos, polyoxomycin, pyrimidine, pyrimidine, oxypyrimidine Phosphorus, azoxystrobin, isopropicol, uracil, etc.; dye raw materials, such as dyes having a trihalogenated pyrimidine core, have good reaction with fibers, and have attracted attention as reactive dyes.
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Amino compound
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Oxy-containing amino compound
Cycloalkylamines, aromatic monoamines, aromatic polyamines and derivatives and salts thereof
Acyclic monoamines, polyamines and their derivatives and salts
Amide compound
Sulfonic acid amino compound
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Alcohols, phenols, phenolic compounds and derivatives
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2-cycloalcohol
Halogenated, sulfonated, nitrated or nitrosated derivatives of alcohols
Extremely halogenated, sulfonated, nitrated or nitrosated derivatives of phenols
Phenol and its halogenated, sulfonated, nitrated or nitrosated derivatives
Acyclic alcohol
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Nitrogen-containing compound
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Nitrile compound
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Organic derivative of hydrazine or hydrazine
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Terpenoid
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Ether compounds and their derivatives
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Ether, ether alcohol
Halogenation, sulfonation, nitration or nitrosation of ethers, ether alcohols, ether phenols
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Aldehyde
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Carboxylic compounds and derivatives
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Cyclic carboxylic acid
Halogenation, sulfonation, nitration or nitrosation of carboxylic acids
Halogenation, sulfonation, nitration or nitration of carboxylic anhydrides
Carboxylic acid halide
Carboxylic esters and their derivatives
Salt of carboxylic acid ester and its derivatives
Acyclic carboxylic acid
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Hydrocarbon compounds and their derivatives
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Aromatic hydrocarbon
Cyclic hydrocarbon
Hydrocarbon sulfonate
Hydrocarbon halide
Hydrocarbon nitrite
Acyclic hydrocarbon
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Ketone compound
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Alkyl ureas and their derivatives and salts
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Inorganic acid ester
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Heterocyclic compound
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Diazo, azo or azo compound
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Organosilicon compound
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Organometallic compound
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Organic palladium
Organic germanium, cobalt, strontium, barium, gallium, germanium, germanium, germanium, germanium, etc.
Organic calcium
Zirconium
Organic potassium
Organic
Organic lithium
Organic
Organic aluminum
Organotin
Organic manganese
Organic sodium
Organic nickel
Organic titanium
Organic iron
Organic copper
Organotin
Organic zinc
Organic
Organic
Organic germanium, mercury, silver, platinum, etc.
Organic germanium, antimony, bismuth, tungsten, antimony, bismuth, lead, vanadium, molybdenum, chromium, antimony, etc.
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Organic sulfur compound
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Organic phosphine compound
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Organometallic salt
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Organic fluorine compound
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Fluorobenzoic acid series
Fluorobenzonitrile series
Fluorobenzaldehyde series
Fluorobenzyl alcohol series
Fluoroanisole series
Fluoroaniline series
Fluorophenylacetic acid series
Fluorophenol series
Fluorobenzoic acid series
Fluoronitrobenzene series
Fluoropyridine series
Potassium fluoroborate series
Fluorobenzyl alcohol series
Fluorotoluene series
Fluorine red series
Fluoroethane series
Fluoropropane series