3-Oxo-dodecan-(2-aminocyclohexanone)
3-Oxo-dodecan-(2-aminocyclohexanone) structure
|
Common Name | 3-Oxo-dodecan-(2-aminocyclohexanone) | ||
|---|---|---|---|---|
| CAS Number | 596104-55-1 | Molecular Weight | 309.44400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H31NO3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Induction and inhibition of Pseudomonas aeruginosa quorum sensing by synthetic autoinducer analogs.
Chemistry and Biology 10(1) , 81-89, (2003) We synthesized a library of Pseudomonas aeruginosa autoinducer analogs with variation targeted to the homoserine lactone (HSL) moiety and discovered a new agonist, 3-oxo-C(12)-(2-aminocyclohexanol), capable of activating LasR as a transcription factor. We rec... |
|
|
P. aeruginosa quorum-sensing systems and virulence.
Curr. Opin. Microbiol. 6 , 56-60, (2003) Quorum sensing is an important mechanism for the regulation of genes in many Gram-negative and Gram-positive bacteria. In the opportunistic pathogen Pseudomonas aeruginosa, the absence of one or more components of the quorum-sensing system results in a signif... |
|
|
Pseudomonas aeruginosa quorum sensing as a potential antimicrobial target.
J. Clin. Invest. 112 , 1460-1465, (2003) Pseudomonas aeruginosa has two complete quorum-sensing systems. Both of these systems have been shown to be important for Pseudomonas virulence in multiple models of infection. Thus, these systems provide unique targets for novel antimicrobial drugs. |
|
|
Construction of an effective screening system for detection of Pseudomonas aeruginosa quorum sensing inhibitors and its application in bioautographic thin-layer chromatography.
Biotechnol. Lett. 33 , 1381-1387, (2011) In Pseudomonas aeruginosa, quorum sensing (QS) regulates dozens of genes and proteins, many of which contribute to the virulence of this pathogen. QS inhibitory (QSI) compounds have been proposed as potential agents for treatment of bacterial infections. To s... |