Journal of Clinical Investigation 2003-11-01

Pseudomonas aeruginosa quorum sensing as a potential antimicrobial target.

Roger S Smith, Barbara H Iglewski

Index: J. Clin. Invest. 112 , 1460-1465, (2003)

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Abstract

Pseudomonas aeruginosa has two complete quorum-sensing systems. Both of these systems have been shown to be important for Pseudomonas virulence in multiple models of infection. Thus, these systems provide unique targets for novel antimicrobial drugs.