(±)-Alliin
(±)-Alliin structure
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Common Name | (±)-Alliin | ||
|---|---|---|---|---|
| CAS Number | 17795-26-5 | Molecular Weight | 177.221 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 416.1±45.0 °C at 760 mmHg | |
| Molecular Formula | C6H11NO3S | Melting Point | N/A | |
| MSDS | USA | Flash Point | 205.5±28.7 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Analytical method for simultaneous determination of bulk and intramolecular (13) C-isotope compositions of acetic acid.
Rapid Commun. Mass Spectrom. 29 , 2337-40, (2015) Headspace solid-phase microextraction (HS-SPME) combined with gas chromatography/pyrolysis-gas chromatography/combustion-isotope ratio mass spectrometry (GC/Py-GC/C-IRMS) was developed for the simultaneous determination of the intramolecular and molecular car... |
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Metabolism, excretion, and pharmacokinetics of S-allyl-L-cysteine in rats and dogs.
Drug Metab. Dispos. 43(5) , 749-55, (2015) The metabolism, excretion, and pharmacokinetics of S-allyl-l-cysteine (SAC), an active key component of garlic supplements, were examined in rats and dogs. A single dose of SAC was administered orally or i.v. to rats (5 mg/kg) and dogs (2 mg/kg). SAC was well... |
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Combination of aqueous two-phase extraction and cation-exchange chromatography: New strategies for separation and purification of alliin from garlic powder
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 957 , 60-7, (2014) In this study, a two-step process combining aqueous two-phase extraction (ATPE) with chromatography was developed for extraction and purification of alliin from garlic powder. The partition coefficient and yield value of alliin in different types of aqueous t... |
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Formulation, high throughput in vitro screening and in vivo functional characterization of nanoemulsion-based intranasal vaccine adjuvants.
PLoS ONE 10 , e0126120, (2015) Vaccine adjuvants have been reported to induce both mucosal and systemic immunity when applied to mucosal surfaces and this dual response appears important for protection against certain pathogens. Despite the potential advantages, however, no mucosal adjuvan... |
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Fluorescent magnetic iron oxide nanoparticles for cardiac precursor cell selection from stromal vascular fraction and optimization for magnetic resonance imaging.
Int. J. Nanomedicine 10 , 711-26, (2015) Fluorescent magnetic iron oxide nanoparticles have been used to label cells for imaging as well as for therapeutic purposes. The purpose of this study was to modify the approach to develop a nanoprobe for cell selection and imaging with a direct therapeutic t... |
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Proteomic analysis of the effects of aged garlic extract and its FruArg component on lipopolysaccharide-induced neuroinflammatory response in microglial cells.
PLoS ONE 9(11) , e113531, (2014) Aged garlic extract (AGE) is widely used as a dietary supplement, and is claimed to promote human health through anti-oxidant/anti-inflammatory activities with hypolipidemic, antiplatelet and neuroprotective effects. Prior studies of AGE have mainly focused o... |
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Conjugation of D-glucosamine to bovine trypsin increases thermal stability and alters functional properties.
Enzyme Microb. Technol. 75-76 , 1-9, (2015) D-Glucosamine was conjugated to bovine trypsin by carbodiimide chemistry, involving a water-soluble carbodiimide and a succinimide ester, with the latter being to increase the yield of the conjugation. Mass spectrometric data suggested that several glycoforms... |
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Molecular characterization of ongoing enzymatic reactions in raw garlic cloves using extractive electrospray ionization mass spectrometry.
Anal. Chem. 87(5) , 2878-83, (2015) Characterization of enzymatic reactions occurring in untreated biological samples is of increasing interest. Herein, the chemical conversion of alliin to allicin, catalyzed by allinase, in raw garlic cloves has been followed in vivo by internal extractive ele... |
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Assessing developmental toxicity of caffeine and sweeteners in medaka (Oryzias latipes).
Springerplus 4 , 486, (2015) The use of artificial sweeteners (ASWs) has increased and become more widespread, and consequently ASWs have appeared in aquatic environments around the world. However, their safety to the health of humans and wildlife remains inconclusive. In this study, usi... |
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In situ allicin generation using targeted alliinase delivery for inhibition of MIA PaCa-2 cells via epigenetic changes, oxidative stress and cyclin-dependent kinase inhibitor (CDKI) expression.
Apoptosis 20 , 1388-409, (2015) Allicin, an extremely active constituent of freshly crushed garlic, is produced upon reaction of substrate alliin with the enzyme alliinase (EC 4.4.1.4). Allicin has been shown to be toxic to several mammalian cells in vitro in a dose-dependent manner. In the... |