Methyl 2-isocyanatobenzoate
Methyl 2-isocyanatobenzoate structure
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Common Name | Methyl 2-isocyanatobenzoate | ||
|---|---|---|---|---|
| CAS Number | 1793-07-3 | Molecular Weight | 177.157 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 267.1±23.0 °C at 760 mmHg | |
| Molecular Formula | C9H7NO3 | Melting Point | 45-49ºC | |
| MSDS | Chinese USA | Flash Point | 124.8±17.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase.
J. Med. Chem. 56(23) , 9457-70, (2013) Heme-regulated inhibitor kinase (HRI), a eukaryotic translation initiation factor 2 alpha (eIF2α) kinase, plays critical roles in cell proliferation, differentiation, and adaptation to cytoplasmic stress. HRI is also a critical modifier of hemoglobin disorder... |
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Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo.
J. Biol. Chem. 284 , 7673-7680, (2009) Retinol-binding protein 4 (RBP4) transports retinol from the liver to extrahepatic tissues, and RBP4 lowering is reported to improve insulin sensitivity in mice. We have identified A1120, a high affinity (K(i) = 8.3 nm) non-retinoid ligand for RBP4, which dis... |
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ortho-Lithiophenyl isocyanide: a versatile precursor for 3H-quinazolin-4-ones and 3H-quinazolin-4-thiones.
Org. Lett. 11(2) , 389-92, (2009) ortho-Lithiophenyl isocyanide has been generated from ortho-bromophenyl isocyanide and successfully employed toward the synthesis of 2-substituted phenyl isocyanides as well as 2,3-disubstituted 3H-quinazoline-4-ones and 3H-quinazolin-4-thiones. |
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Chemistry of 4H-3, 1-Benzoxazin-4-ones. El-Mekabaty A.
Int. J. Mod. Org. Chem. 2(2) , 81-121, (2013)
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