Taurochenodeoxycholic acid sodium salt
Taurochenodeoxycholic acid sodium salt structure
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Common Name | Taurochenodeoxycholic acid sodium salt | ||
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| CAS Number | 6009-98-9 | Molecular Weight | 521.685 | |
| Density | 1.164 g/mL at 25 °C(lit.) | Boiling Point | 215 °C(lit.) | |
| Molecular Formula | C26H44NNaO6S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 195 °F | |
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[Familial amyloid polyneuropathies: therapeutic issues].
Bull. Acad. Natl. Med. 196(7) , 1333-45; discussion 1345-7, (2012) Patients with familial amyloidpolyneuropathies (FAP) require multidisciplinary neurologic and cardiologic management, including specific treatments to control the progression of systemic amyloidogenesis, symptomatic treatment of peripheral and autonomic neuro... |
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Bile acids repress hypoxia-inducible factor 1 signaling and modulate the airway immune response.
Infect. Immun. 82(9) , 3531-41, (2014) Gastroesophageal reflux (GER) frequently occurs in patients with respiratory disease and is particularly prevalent in patients with cystic fibrosis. GER is a condition in which the duodenogastric contents of the stomach leak into the esophagus, in many cases ... |
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Metabolomics reveals novel biomarkers of illegal 5-nitromimidazole treatment in pigs. Further evidence of drug toxicity uncovered.
Food Chem. 199 , 876-84, (2016) The aim of the study was to investigate the potential of a metabolomics platform to distinguish between pigs treated with ronidazole, dimetridazole and metronidazole and non-medicated animals (controls), at two withdrawal periods (day 0 and 5). Livers from ea... |
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Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids.
PLoS ONE 11 , e0149603, (2016) Biofilms are a ubiquitous feature of microbial community structure in both natural and host environments; they enhance transmission and infectivity of pathogens and provide protection from human defense mechanisms and antibiotics. However, few natural product... |
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Taurine may not alleviate hyperglycemia-mediated endoplasmic reticulum stress in human adipocytes.
Adv. Exp. Med. Biol. 775 , 395-403, (2013) In obesity and diabetes, adipocytes show significant endoplasmic reticulum (ER) stress. Hyperglycemia-induced ER stress has not been studied in adipocyte differentiation and adipokine expression. Taurine has been known to protect the cells against ER stress. ... |
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Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut.
Proc. Natl. Acad. Sci. U. S. A. 111(20) , 7421-6, (2014) Alterations in the gastrointestinal microbiota have been implicated in obesity in mice and humans, but the key microbial functions influencing host energy metabolism and adiposity remain to be determined. Despite an increased understanding of the genetic cont... |
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Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death.
Lab. Invest. 94(12) , 1419-30, (2014) Ulcerative colitis (UC) is characterized by increased epithelial cell death and subsequent breakdown of the intestinal epithelial barrier, which perpetuates chronic intestinal inflammation. Since fecal bile acid dysmetabolism is associated with UC and taurour... |
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Competitive Solubilization of Cholesterol/Cholesteryl Oleate and Seven Species of Sterol/Stanol in Model Intestinal Solution System.
J. Oleo Sci. 64 , 783-91, (2015) The addition of plant sterols/stanols (sterols or stanols) can reduce the solubilization of cholesterol in a model intestinal solution system. We studied the molecular structure of seven different sterols/stanols and the effect they had on the solubilization ... |
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Aberrant endoplasmic reticulum stress in vascular smooth muscle increases vascular contractility and blood pressure in mice deficient of AMP-activated protein kinase-α2 in vivo.
Arterioscler. Thromb. Vasc. Biol. 33(3) , 595-604, (2013) The endoplasmic reticulum (ER) plays a critical role in ensuring proper folding of newly synthesized proteins. Aberrant ER stress is reported to play a causal role in cardiovascular diseases. However, the effects of ER stress on vascular smooth muscle contrac... |
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Chemical chaperones reduce ionizing radiation-induced endoplasmic reticulum stress and cell death in IEC-6 cells.
Biochem. Biophys. Res. Commun. 450(2) , 1005-9, (2014) Radiotherapy, which is one of the most effective approaches to the treatment of various cancers, plays an important role in malignant cell eradication in the pelvic area and abdomen. However, it also generates some degree of intestinal injury. Apoptosis in th... |