2,2-dimethylvaleric acid
2,2-dimethylvaleric acid structure
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Common Name | 2,2-dimethylvaleric acid | ||
|---|---|---|---|---|
| CAS Number | 1185-39-3 | Molecular Weight | 130.18500 | |
| Density | 0.918 g/mL at 20 °C(lit.) | Boiling Point | 200-205°C | |
| Molecular Formula | C7H14O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 200-205°C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasma.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 862(1-2) , 168-74, (2008) 2,2-Dimethylbutyrate (DMB) is a potential treatment for thalassemia and hemoglobinopathies. To facilitate pharmacokinetic evaluation of DMB, we developed an LC-MS assay and quantitated DMB in plasma of rats after an oral dose of 500mg/kg. After acetonitrile p... |
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Effects of branched-chain fatty acids on GABA-degradation and behavior: further evidence for a role of GABA in quasi-morphine abstinence behavior.
Pharmacol. Biochem. Behav. 13(6) , 843-9, (1980) An increase in GABA-ergic activity has been implicated in the initiation of quasi-morphine abstinence behavior by di-n-propylacetate (DPA). Two structural analogues of DPA, namely, the branched-chain-fatty acid 2-methyl, 2-ethylcaproic acid and 2,2-dimethylva... |
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Effects of the lipid regulator drug gemfibrozil: A toxicological and behavioral perspective.
Aquat. Toxicol. 170 , 355-64, (2016) Pharmaceuticals are emerging contaminants as their worldwide consumption increases. Fibrates such as gemfibrozil (GEM) are used in human medicine to reduce blood concentrations of cholesterol and triacylglycerol and also are some of the most frequently report... |
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Oxidative metabolism of 4-aminobutyrate by rat brain mitochondria: inhibition by branched-chain fatty acid.
J. Neurochem. 34(1) , 197-202, (1980) The oxidation of 4-aminobutyric acid (GABA) by nonsynaptosomal mitochondria isolated from rat forebrain and the inhibition of this metabolism by the branched-chain fatty acids 2-methyl-2-ethyl caproate (MEC) and 2.2-dimethyl valerate (DMV) were studied. The r... |